Name: HGH Fragment 176-191
Brand: Lilipeptide
SKU: LILI-hgh-fragment-176-191
Price: 63.00 USD
Availability: InStock

HGH Fragment 176-191 at a glance

HGH Fragment 176-191 is a short synthetic peptide matching the final stretch of human growth hormone, a segment that contains a disulfide-linked loop near the C-terminus. Researchers at Monash University in Australia investigated this region after finding that it appeared to carry some of growth hormone's effects on fat metabolism without its growth-promoting activity. A closely related analog, AOD-9604, came out of the same research program and was later taken into clinical testing.

Price and availability

This is Lilipeptide‘s listing, dispatched from China. It is listed at $63.00. Checkout goes into escrow first; the funds move to Lilipeptide once delivery is confirmed.

This listing: Lilipeptide HGH Fragment 176-191

Brand: Lilipeptide
Also sold by: Kensington Biosciences 10mg $400.00 · TFC Peptides 2mg $45.00 · TFC Peptides 5mg $85.00 · Lianhua Peptide Co. 5mg $78.00 · SSRBIO 5mg $78.00 · European Peptide Sciences 5mg $370.00

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

The fragment is proposed to act through a different route from intact growth hormone. In obese rodent studies, it was reported to increase lipolysis and reduce lipogenesis in fat tissue, apparently without activating growth hormone receptor signaling, raising IGF-1, or impairing insulin sensitivity. Some papers suggested involvement of beta-adrenergic pathways in fat cells, but the receptor responsible has not been identified with confidence. Much of the mechanistic understanding rests on a small number of studies, many of them using the AOD-9604 analog rather than the fragment itself.

Research and regulatory status

Evidence for the fragment itself is preclinical. The related AOD-9604 analog went into human trials for obesity, and its developer stopped that program after later-stage results did not show meaningful weight loss compared with placebo. Independent replication of the fat-metabolism findings in people is lacking. HGH Fragment 176-191 is not an approved medicine, and growth hormone fragments are prohibited under sports anti-doping rules.

Checking the lab data

A credible report should confirm identity by mass spectrometry against the mass calculated for the stated sequence, and the vendor should say exactly which sequence and modifications the product carries, since this fragment and AOD-9604 are often conflated. HPLC purity should come from a lot-specific chromatogram, ideally showing the intact disulfide rather than reduced or dimerized forms. The lyophilized cake should be white.

No independent report is attached to this listing yet. You can compare brands that publish one on the marketplace or browse the lab reports directory.

Listing details

Compound: HGH Fragment 176-191
Sold by: Lilipeptide
Ships from: China
Lab report: Not yet published

Storage and preparation

Store sealed and as the label directs, away from heat and direct light. Discard anything with a broken seal or cloudy contents.

Buyer questions

Is HGH Fragment 176-191 the same as AOD-9604?

They are very closely related. AOD-9604 is described as growth hormone residues 177 to 191 with a tyrosine added at the N-terminus, and because residue 176 of growth hormone is itself a tyrosine, the two can be identical or nearly so depending on how a vendor defines them. A lab report with sequence and mass resolves the question.

Does the fragment raise IGF-1 like growth hormone?

Rodent studies of the fragment and its analog reported no meaningful rise in IGF-1 and no growth-promoting effects, which is why the region attracted interest as a way to separate metabolic from growth activity. Those observations come from a limited set of studies and have not been confirmed by independent human research.

When does Lilipeptide get paid?

Only after you confirm delivery. Until then the payment is held in escrow, and you can open a claim if anything is wrong with the order.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.