Name: Adipotide
Brand: Lilipeptide
SKU: LILI-adipotide
Price: 210.00 USD
Availability: InStock

Adipotide at a glance

Adipotide, catalogued as FTPP, was designed by researchers at the University of Texas MD Anderson Cancer Center who used phage-display screening to find peptides that home to fat-tissue vasculature. The construct joins a cyclic targeting motif, CKGGRAKDC, to a pro-apoptotic sequence built from D-amino acids, D(KLAKLAK)2. The D-form backbone resists proteases, and the pro-apoptotic part is meant to act only after the targeting motif has carried it to the intended cells.

Price and availability

This is Lilipeptide‘s listing, dispatched from China. It is listed at $210.00. As with every order here, the brand is paid only after you confirm delivery.

This listing: Lilipeptide Adipotide

Brand: Lilipeptide
Also sold by: Lab77 Peptides 10mg $77.00 · Uther Peptide 10mg $165.00 · TFC Peptides 2mg $65.00 · TFC Peptides 5mg $140.00 · HK Peptide 5mg $150.00

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

The targeting motif is reported to bind prohibitin, a protein found on the surface of endothelial cells lining blood vessels in white adipose tissue, possibly in partnership with annexin A2. After binding, the conjugate is thought to be internalized, where the KLAKLAK domain disrupts mitochondrial membranes and sets off apoptosis in those endothelial cells. Loss of vascular supply is proposed to cause the fat cells downstream to shrink or die. The approach is therefore indirect, acting on vasculature rather than on adipocyte receptors or metabolic hormones.

Research and regulatory status

The founding mouse study reported fat loss in obese animals, and a later study in obese rhesus monkeys described reduced body weight, smaller waist measurements and improved insulin sensitivity. That primate work also recorded dose-dependent kidney changes, described as reversible, which shaped later discussion of the compound. Development as a human obesity treatment did not proceed, and Adipotide remains an unapproved experimental agent with no completed efficacy trials in people.

Checking the lab data

The two-domain structure makes identity testing especially important. Mass spectrometry should show a mass consistent with the full conjugate, expected near 2611 g/mol, and HPLC should show one dominant peak rather than separate targeting and effector fragments. Confirmation that the cyclic disulfide has formed, and of D-amino-acid content where the method allows, adds assurance. The lyophilized cake should be white and intact.

This listing has no third-party report on file yet. The lab reports directory and the marketplace show which brands do publish testing.

Listing details

Compound: Adipotide
Synonyms: FTPP
Class: Proapoptotic peptidomimetic (fat-vasculature targeting)
Format: Lyophilized (freeze-dried) powder
Sold by: Lilipeptide
Ships from: China
Lab report: Not yet published

Storage and preparation

Keep unopened freeze-dried vials cold, sealed and out of the light; moisture is what degrades a lyophilized cake fastest. After reconstitution, refrigerate the solution and work within the stability window your protocol sets.

Buyer questions

What does phage display have to do with Adipotide?

Phage display screens huge libraries of peptides displayed on bacteriophage surfaces. Researchers introduced such libraries into animals and recovered the peptides that accumulated in fat-tissue blood vessels. The motif that emerged became Adipotide's targeting domain, so the compound is a product of that vascular-mapping work rather than conventional receptor-based design.

Why are kidney findings mentioned in Adipotide research?

The primate study reported dose-related changes in kidney function and structure that improved after treatment stopped. Because the pro-apoptotic domain can affect any cells it reaches, investigators treated selectivity as a central open question. These findings are part of why the compound stayed at the experimental stage.

When does Lilipeptide get paid?

Only after you confirm delivery. Until then the payment is held in escrow, and you can open a claim if anything is wrong with the order.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.