Hexarelin Acetate

Hexarelin at a glance

Hexarelin is a synthetic hexapeptide from the growth hormone-releasing peptide (GHRP) family, closely related in structure to GHRP-6. Its sequence is His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2; the methyl group on the D-tryptophan was added to improve stability and potency. It was developed in Europe before the endogenous ligand ghrelin had been discovered, and it remains a reference compound in secretagogue research. Supplies are typically a white lyophilized powder.

Price and availability

Lilipeptide lists this listing, shipped from China. It is listed at $110.00. As with every order here, the brand is paid only after you confirm delivery.

What it is studied for

Hexarelin is an agonist of the growth hormone secretagogue receptor type 1a, the receptor later identified as the target of ghrelin. Activation in the pituitary and hypothalamus triggers robust growth hormone release, and studies also report rises in prolactin, ACTH and cortisol, a broader endocrine footprint than more selective secretagogues show. Separately, hexarelin binds the scavenger receptor CD36, which is expressed in heart and blood vessels; this interaction has been proposed to explain cardiac effects seen in animal models independent of growth hormone. Prolonged exposure is reported to blunt the GH response, a phenomenon described as desensitization.

Research and regulatory status

Human studies in the 1990s and early 2000s examined hexarelin's endocrine effects in healthy volunteers, older adults and people with growth hormone deficiency, and small studies explored cardiac function. Animal work on ischemia, cardiomyopathy and cardiac fibrosis followed. It never progressed to regulatory approval, and as a growth hormone secretagogue it falls under anti-doping prohibitions. Current research interest centers on its CD36 activity and cardiovascular mechanisms.

Checking the lab data

Mass spectrometry should match the expected mass of the six-residue sequence including the methylated D-tryptophan, which distinguishes hexarelin from GHRP-6 and other close relatives. HPLC purity should be reported with a chromatogram, ideally using a method able to separate stereoisomer impurities, since two residues are D-amino acids. Batch number, test date and laboratory name should be present. Expect a white lyophilized cake.

This listing has no third-party report on file yet. The lab reports directory and the marketplace show which brands do publish testing.

Listing details

Compound

Hexarelin

Sold by

Lilipeptide

Ships from

China

Lab report

Not yet published

Storage and preparation

Store sealed and as the label directs, away from heat and direct light. Discard anything with a broken seal or cloudy contents.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.