Tesamorelin

Tesamorelin at a glance

Tesamorelin, coded TH9507 during development, reproduces the full 44-residue sequence of human growth hormone-releasing hormone and caps the N-terminus with a trans-3-hexenoyl group. Native GHRH is cleaved rapidly by dipeptidyl peptidase-4, and the cap is intended to resist that cleavage while keeping receptor activity intact. The molecule has the formula C221H366N72O67S and a molecular weight near 5136 g/mol. Listings on this marketplace supply it as lyophilized powder for laboratory study.

Price and availability

A listing from Vital Edge Science, shipped from Australia. It is listed at $97.00. Funds stay in escrow and are released to Vital Edge Science only when you mark the order as received.

What it is studied for

The peptide is a GHRH-receptor agonist. Binding to these receptors on anterior pituitary somatotrophs activates cAMP signaling, which promotes both synthesis and pulsed secretion of growth hormone; circulating GH then prompts the liver to raise IGF-1. Because the signal enters at the hypothalamic-pituitary level, somatostatin tone and IGF-1 negative feedback continue to shape output, a feature researchers often contrast with giving exogenous GH. Work in this area also looks at how the stimulated GH pulses relate to lipolysis in visceral fat depots, though the full chain from pulse pattern to tissue effect is still under study.

Research and regulatory status

Tesamorelin holds an FDA approval for reducing excess abdominal fat in people with HIV-associated lipodystrophy, and the randomized trials behind that approval measured visceral adipose tissue by imaging. Later investigator-led studies explored liver fat, cognition in older adults and other metabolic endpoints, with mixed and still-maturing results. Research-grade tesamorelin sold through GLP1 Forum Escrow is not the pharmaceutical product; it is offered for laboratory work, and quality varies by manufacturer, so batch reports deserve a close read.

Checking the lab data

For a 44-residue peptide, identity should rest on mass spectrometry showing a mass consistent with roughly 5136 Da, often presented as a deconvoluted electrospray spectrum. HPLC purity should come with the trace so related impurities, such as deletion sequences or oxidized methionine forms, are visible rather than summarized away. A report should also state net peptide content, describe the cake as white and intact, and tie every result to a batch number printed on the vial.

An independent lab report is attached to this listing, and the panel above shows the measured result next to the labelled amount.

Listing details

Compound

Tesamorelin

Synonyms

TH9507

Class

Growth hormone-releasing hormone (GHRH) analogue

Format

Lyophilized (freeze-dried) powder

Molecular formula

C₂₂₁H₃₆₆N₇₂O₆₇S

Molecular weight

5136 g/mol

Sold by

Vital Edge Science

Ships from

Australia

Lab report

Independent report attached

Storage and preparation

Keep unopened freeze-dried vials cold, sealed and out of the light; moisture is what degrades a lyophilized cake fastest. After reconstitution, refrigerate the solution and work within the stability window your protocol sets.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.