Teriparatide 750mcg (10 Vials / Kit)

Teriparatide at a glance

Teriparatide is identical to the first 34 amino acids of human parathyroid hormone, which in full is an 84-residue polypeptide secreted by the parathyroid glands. Pharmaceutical teriparatide is typically produced by recombinant expression in E. coli, while research material may be recombinant or chemically synthesized; either route yields the same sequence. Introduced by Eli Lilly, it became the first approved bone-building osteoporosis treatment, and biosimilar and generic versions now exist in many markets.

Price and availability

Sold by Uther Peptide and sent from China, this listing is a kit of 10 vials at 750mcg each (7.5 mg in total). At $100.00 for the kit, that works out to $13.33 per mg. 2 brands currently sell Teriparatide here, so compare their listings before ordering. Your payment waits in escrow until you confirm the parcel arrived, and only then is it released to the brand.

What it is studied for

Teriparatide binds the PTH1 receptor on osteoblasts, osteocytes and renal tubular cells. Signaling runs mainly through Gs and cyclic AMP, with additional Gq and beta-arrestin pathways. In bone, brief receptor activation is reported to reduce osteoblast apoptosis, recruit lining cells into active bone formation and suppress sclerostin from osteocytes, which releases Wnt signaling. Sustained receptor activation, by contrast, favors RANKL-driven osteoclast activity and net resorption. This exposure-dependent duality is the central mechanistic theme in teriparatide research, and it is often contrasted with the PTHrP-derived analogue abaloparatide.

Research and regulatory status

Teriparatide has one of the deepest clinical records of any peptide in bone medicine, built on large fracture trials in postmenopausal women and later studies in men and in glucocorticoid-induced osteoporosis. Early rat studies reported osteosarcoma with high, prolonged exposure, which shaped its labeling for years. Laboratory research continues on fracture healing, osteocyte biology and receptor signaling. Research-grade material is not the approved product and is not interchangeable with it.

Checking the lab data

Mass spectrometry should match the theoretical mass of PTH(1-34). Teriparatide contains methionines that oxidize readily, so the report should note any +16 Da species, and deamidation products are worth flagging too. HPLC purity should be backed by a chromatogram. The report should also state whether the peptide is recombinant or synthetic, and include a batch number and test date. Expect a white lyophilized cake.

No independent report is attached to this listing yet. You can compare brands that publish one on the marketplace or browse the lab reports directory.

Listing details

Compound

Teriparatide

Synonyms

PTH(1-34), Parathyroid Hormone Fragment

Class

Recombinant parathyroid hormone fragment (34 amino acids)

Format

Lyophilized (freeze-dried) powder

Vial strength

750mcg

Vials per kit

10

Total content

7.5 mg

Price per mg

$13.33

Sold by

Uther Peptide

Ships from

China

Lab report

Not yet published

Storage and preparation

Keep unopened freeze-dried vials cold, sealed and out of the light; moisture is what degrades a lyophilized cake fastest. After reconstitution, refrigerate the solution and work within the stability window your protocol sets.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.