Teriparatide 10mg (10 Vials / Kit)

Teriparatide at a glance

Teriparatide is identical to the first 34 amino acids of human parathyroid hormone, which in full is an 84-residue polypeptide secreted by the parathyroid glands. Pharmaceutical teriparatide is typically produced by recombinant expression in E. coli, while research material may be recombinant or chemically synthesized; either route yields the same sequence. Introduced by Eli Lilly, it became the first approved bone-building osteoporosis treatment, and biosimilar and generic versions now exist in many markets.

Price and availability

A kit of 10 vials at 10mg each (100 mg in total) from TFC Peptides, shipped from Tianjin, China. At $180.00 for the kit, that works out to $1.80 per mg. Of the 2 Teriparatide listings on the marketplace, from 2 brands, this is the lowest price per mg. As with every order here, the brand is paid only after you confirm delivery.

What it is studied for

Teriparatide binds the PTH1 receptor on osteoblasts, osteocytes and renal tubular cells. Signaling runs mainly through Gs and cyclic AMP, with additional Gq and beta-arrestin pathways. In bone, brief receptor activation is reported to reduce osteoblast apoptosis, recruit lining cells into active bone formation and suppress sclerostin from osteocytes, which releases Wnt signaling. Sustained receptor activation, by contrast, favors RANKL-driven osteoclast activity and net resorption. This exposure-dependent duality is the central mechanistic theme in teriparatide research, and it is often contrasted with the PTHrP-derived analogue abaloparatide.

Research and regulatory status

Teriparatide has one of the deepest clinical records of any peptide in bone medicine, built on large fracture trials in postmenopausal women and later studies in men and in glucocorticoid-induced osteoporosis. Early rat studies reported osteosarcoma with high, prolonged exposure, which shaped its labeling for years. Laboratory research continues on fracture healing, osteocyte biology and receptor signaling. Research-grade material is not the approved product and is not interchangeable with it.

Checking the lab data

Mass spectrometry should match the theoretical mass of PTH(1-34). Teriparatide contains methionines that oxidize readily, so the report should note any +16 Da species, and deamidation products are worth flagging too. HPLC purity should be backed by a chromatogram. The report should also state whether the peptide is recombinant or synthetic, and include a batch number and test date. Expect a white lyophilized cake.

This listing has no third-party report on file yet. The lab reports directory and the marketplace show which brands do publish testing.

Listing details

Compound

Teriparatide

Synonyms

PTH(1-34), Parathyroid Hormone Fragment

Class

Recombinant parathyroid hormone fragment (34 amino acids)

Format

Lyophilized (freeze-dried) powder

Vial strength

10mg

Vials per kit

10

Total content

100 mg

Price per mg

$1.80

Sold by

TFC Peptides

Ships from

Tianjin, China

Lab report

Not yet published

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 10 mg vial dissolved in 2 mL gives 5 mg/mL, or 10 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.