Name: SS-31 50mg (10 Vials / Kit)
Brand: TFC Peptides
SKU: TFC-2S50
Price: 325.00 USD
Availability: InStock

SS-31 (Elamipretide) at a glance

SS-31 came out of a series of small designed peptides named after Hazel Szeto and Peter Schiller, the researchers who developed them. Its four residues, D-Arg-Dmt-Lys-Phe-NH2, alternate positive charges with aromatic rings, a pattern that lets the molecule pass through cell membranes and collect on the inner membrane of mitochondria without a carrier. The D-arginine and dimethyltyrosine (Dmt) building blocks help it resist enzymatic breakdown. In clinical development it carries the name elamipretide.

Price and availability

Sold by TFC Peptides and sent from Tianjin, China, this listing is a kit of 10 vials at 50mg each (500 mg in total). $325.00 buys the whole kit, which is $0.65/mg. Of the 22 SS-31 (Elamipretide) listings on the marketplace, from 17 brands, this is the 2nd-lowest price per mg. Funds stay in escrow and are released to TFC Peptides only when you mark the order as received.

This listing: TFC Peptides SS-31 (Elamipretide)

Brand: TFC Peptides
Kit: 10 vials × 50 mg (500 mg in total)
Price per vial: $32.50
Price per mg: $0.65
Other strengths: 10mg $85.00
Also sold by: Uther Peptide 50mg $350.00 · HK Peptide 50mg $350.00 · Lilipeptide SS-31 $120.00 · Lab77 Peptides 10mg $38.00 · Imperial Peptides 10mg $44.00 · HK Peptide 10mg $75.00

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

Its main proposed target is cardiolipin, a lipid found almost exclusively in the inner mitochondrial membrane, where it helps hold the respiratory chain complexes in place and shapes the folded cristae. SS-31 is thought to bind cardiolipin and protect it from peroxidation. In experimental systems this has been linked to better-organized cristae, more efficient electron transfer and ATP output, and less leakage of reactive oxygen species. Because the peptide acts at the membrane rather than through a cell-surface receptor, it is studied as a tool for probing mitochondrial bioenergetics directly.

Research and regulatory status

As elamipretide, the peptide has been tested in human trials in primary mitochondrial myopathy, Barth syndrome, heart failure and age-related eye disease, with mixed results across indications. In the United States it received accelerated approval for Barth syndrome, a rare inherited mitochondrial disorder, while other uses remain investigational. Preclinical studies cover ischemia-reperfusion injury, kidney disease and aging models. Research-grade SS-31 is not the approved medicine and is not interchangeable with it.

Checking the lab data

Because SS-31 is small, a mass spectrometry result near the listed 639.8 g/mol is a clear identity check, read alongside HPLC purity with the chromatogram. Swapping dimethyltyrosine for plain tyrosine would show as a mass difference, but the D-arginine configuration cannot be seen by mass alone, so chiral analysis or a supplier statement on stereochemistry adds confidence. Expect measured content per vial, a batch number, and a description of a white freeze-dried cake.

This listing has no third-party report on file yet. The lab reports directory and the SS-31 (Elamipretide) page show which brands do publish testing.

Listing details

Compound: SS-31 (Elamipretide)
Synonyms: Elamipretide, Bendavia, MTP-131
Class: Mitochondria-targeted tetrapeptide
Format: Lyophilized (freeze-dried) powder
Molecular formula: C₃₂H₄₉N₉O₅
Molecular weight: 639.8 g/mol
Vial strength: 50mg
Vials per kit: 10
Total content: 500 mg
Price per mg: $0.65
Sold by: TFC Peptides
Ships from: Tianjin, China
Lab report: Not yet published

Storage and preparation

Keep unopened freeze-dried vials cold, sealed and out of the light; moisture is what degrades a lyophilized cake fastest. After reconstitution, refrigerate the solution and work within the stability window your protocol sets.

Concentration arithmetic: one 50 mg vial dissolved in 2 mL gives 25 mg/mL, or 50 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

What is cardiolipin?

Cardiolipin is a distinctive phospholipid concentrated in the inner mitochondrial membrane. It helps anchor the protein complexes of the electron transport chain and supports the folded cristae structure. Damage to cardiolipin is associated with mitochondrial dysfunction in many disease models, which is why compounds that bind it attract research interest.

Why does SS-31 use unusual amino acids?

The D-arginine at the start of the chain and the dimethyltyrosine beside it are not standard protein building blocks. They make the peptide harder for enzymes to cleave and tune how strongly it interacts with membranes. Those choices help explain why such a short chain can stay intact long enough to reach mitochondria in experimental models.

How much SS-31 (Elamipretide) is in this listing?

10 vials of 50mg each — 500 mg in all. Where a lab report exists, the testing panel above shows what the brand's tested sample actually measured.

When does TFC Peptides get paid?

Only after you confirm delivery. Until then the payment is held in escrow, and you can open a claim if anything is wrong with the order.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.