Name: KissPeptin-10 5mg (10 Vials / Kit)
Brand: TFC Peptides
SKU: TFC-KS5
Price: 45.00 USD
Availability: InStock

Kisspeptin-10 at a glance

Kisspeptins are a family of peptides cut from a single precursor encoded by the KISS1 gene, which was first described in cancer research as a metastasis suppressor; the longest form was named metastin. Kisspeptin-10, also listed as KP-10 or metastin (45-54), is the C-terminal decapeptide shared by all of them, and its amidated terminus is essential for receptor binding. It is supplied here as freeze-dried powder for in vitro and animal research.

Price and availability

A kit of 10 vials at 5mg each (50 mg in total) from TFC Peptides, shipped from Tianjin, China. $45.00 buys the whole kit, which is $0.90/mg. 10 brands sell Kisspeptin-10 on GLP1 Forum Escrow, with a typical price of $0.80–$1.20 per mg (median $0.90); this listing is inside that range. Your payment waits in escrow until you confirm the parcel arrived, and only then is it released to the brand.

This listing: TFC Peptides Kisspeptin-10

Brand: TFC Peptides
Kit: 10 vials × 5 mg (50 mg in total)
Price per vial: $4.50
Price per mg: $0.90
Other strengths: 10mg $70.00
Also sold by: HK Peptide 5mg $50.00 · Cyprus Peptides 5mg $97.00 · UWA Biotech 10mg $42.00 · Sulan Bio 10mg $120.00 · HPEBIO 10mg $65.00 · Lilipeptide KissPeptin-10 $84.00

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

KP-10 is an agonist of KISS1R, a G protein-coupled receptor previously called GPR54. In the hypothalamus these receptors sit on GnRH neurons, and activation through Gq signaling depolarizes those cells and triggers GnRH release into the portal circulation. The pituitary then secretes LH and, to a lesser extent, FSH. Kisspeptin neurons in the arcuate nucleus are also thought to help generate GnRH pulses together with neurokinin B and dynorphin. Beyond reproduction, receptor expression in placenta, pancreas and blood vessels has prompted exploratory studies of other roles, which remain far less developed.

Research and regulatory status

The finding that loss-of-function mutations in the receptor cause failed puberty in humans made kisspeptin central to reproductive endocrinology. Since then, investigator-led human studies have infused kisspeptin peptides to probe LH responses, and some have explored their use in triggering egg maturation during assisted reproduction. Those studies are experimental, and kisspeptin-10 is not an approved drug. On this marketplace it is listed for laboratory use, where it serves mainly as a tool for testing receptor activity and hormone-axis responses.

Checking the lab data

Mass spectrometry should match the expected mass for the amidated decapeptide; a free-acid version differs by about one dalton and is a known synthesis error worth ruling out. Buyers should also check that the sequence printed on the report matches the published kisspeptin-10 sequence, since catalogue descriptions sometimes carry errors. HPLC purity with a chromatogram, peptide content, a white cake and a batch number matching the vial should all be present.

This listing has no third-party report on file yet. The lab reports directory and the marketplace show which brands do publish testing.

Listing details

Compound: Kisspeptin-10
Synonyms: KP-10, Metastin (45-54)
Class: Reproductive-axis neuropeptide (decapeptide)
Format: Lyophilized (freeze-dried) powder
Vial strength: 5mg
Vials per kit: 10
Total content: 50 mg
Price per mg: $0.90
Sold by: TFC Peptides
Ships from: Tianjin, China
Lab report: Not yet published

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 5 mg vial dissolved in 2 mL gives 2.5 mg/mL, or 5 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Why is the C-terminal amide important for kisspeptin-10?

Kisspeptins belong to the RF-amide peptide family, named for an arginine-phenylalanine pair ending in an amide group. Structure-activity studies indicate that this amidated end is required for strong KISS1R binding, so a version synthesized with a free carboxylic acid would be expected to show markedly reduced activity in receptor assays.

Why was KISS1 first known as a cancer gene?

The gene was identified in melanoma research because restoring its expression reduced metastatic spread in experimental models, which is how the name metastin arose. Its role in reproduction emerged later, when receptor mutations were linked to absent puberty. Both lines of research continue today, but they ask quite different questions.

How much Kisspeptin-10 is in this listing?

10 vials of 5mg each — 50 mg in all. Where a lab report exists, the testing panel above shows what the brand's tested sample actually measured.

What if the parcel never arrives?

Open a claim from your order page. The payment is still in escrow at that point, so a claim decided in your favour is refunded to your Escrow Wallet.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.