Kisspeptin 10mg (10 Vials / Kit)

Kisspeptin-10 at a glance

Kisspeptins are a family of peptides cut from a single precursor encoded by the KISS1 gene, which was first described in cancer research as a metastasis suppressor; the longest form was named metastin. Kisspeptin-10, also listed as KP-10 or metastin (45-54), is the C-terminal decapeptide shared by all of them, and its amidated terminus is essential for receptor binding. It is supplied here as freeze-dried powder for in vitro and animal research.

Price and availability

Sold by HPEBIO and sent from China, this listing is a kit of 10 vials at 10mg each (100 mg in total). At $65.00 for the kit, that works out to $0.65 per mg. Of the 12 Kisspeptin-10 listings on the marketplace, from 10 brands, this is the lowest price per mg. Funds stay in escrow and are released to HPEBIO only when you mark the order as received.

What it is studied for

KP-10 is an agonist of KISS1R, a G protein-coupled receptor previously called GPR54. In the hypothalamus these receptors sit on GnRH neurons, and activation through Gq signaling depolarizes those cells and triggers GnRH release into the portal circulation. The pituitary then secretes LH and, to a lesser extent, FSH. Kisspeptin neurons in the arcuate nucleus are also thought to help generate GnRH pulses together with neurokinin B and dynorphin. Beyond reproduction, receptor expression in placenta, pancreas and blood vessels has prompted exploratory studies of other roles, which remain far less developed.

Research and regulatory status

The finding that loss-of-function mutations in the receptor cause failed puberty in humans made kisspeptin central to reproductive endocrinology. Since then, investigator-led human studies have infused kisspeptin peptides to probe LH responses, and some have explored their use in triggering egg maturation during assisted reproduction. Those studies are experimental, and kisspeptin-10 is not an approved drug. On this marketplace it is listed for laboratory use, where it serves mainly as a tool for testing receptor activity and hormone-axis responses.

Checking the lab data

Mass spectrometry should match the expected mass for the amidated decapeptide; a free-acid version differs by about one dalton and is a known synthesis error worth ruling out. Buyers should also check that the sequence printed on the report matches the published kisspeptin-10 sequence, since catalogue descriptions sometimes carry errors. HPLC purity with a chromatogram, peptide content, a white cake and a batch number matching the vial should all be present.

This listing has an independent lab report attached; the testing panel above summarises what the tested sample contained against its label.

Listing details

Compound

Kisspeptin-10

Synonyms

KP-10, Metastin (45-54)

Class

Reproductive-axis neuropeptide (decapeptide)

Format

Lyophilized (freeze-dried) powder

Vial strength

10mg

Vials per kit

10

Total content

100 mg

Price per mg

$0.65

Sold by

HPEBIO

Ships from

China

Lab report

Independent report attached

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 10 mg vial dissolved in 2 mL gives 5 mg/mL, or 10 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.