Selank 5mg

Selank at a glance

Selank is a synthetic seven-amino-acid peptide, Thr-Lys-Pro-Arg-Pro-Gly-Pro. Its first four residues reproduce tuftsin, a short immunoactive fragment of the immunoglobulin G heavy chain; the trailing Pro-Gly-Pro motif was appended to slow breakdown by peptidases. The compound came out of Russian academic research and is registered as a medicine in Russia, though it has no approval in the United States or the European Union. Research supplies arrive as a white lyophilized powder.

Price and availability

A single 5mg vial from Imperial Peptides, shipped from Australia. The price is $19.00, or $3.80 per milligram of peptide. Across 18 brands listing Selank here, the middle half of prices falls between $0.693 and $3.80 per mg; this kit is inside that range. Your payment waits in escrow until you confirm the parcel arrived, and only then is it released to the brand.

What it is studied for

Proposed mechanisms span the nervous and immune systems. In rodent work, Selank has been reported to influence GABAergic transmission, possibly by modulating how GABA-A receptors respond to their ligands rather than occupying the benzodiazepine site directly. Other papers describe changes in serotonin and dopamine metabolism, shifts in hippocampal brain-derived neurotrophic factor expression, and inhibition of enkephalin-degrading enzymes, which would prolong endogenous opioid peptide signaling. On the immune side, its tuftsin heritage links it to macrophage activity, and studies have measured altered interleukin-6 and other cytokine transcripts. None of these pathways has been established as the primary mode of action.

Research and regulatory status

Most Selank papers originate from a small network of Russian institutions, and many appear in Russian-language journals. The published work includes rodent anxiety and memory paradigms, gene-expression studies, and small clinical reports in patients with anxiety disorders associated with its domestic registration. Independent Western replication remains limited, and large double-blind trials of the kind the FDA or EMA would require have not been reported. Outside Russia, it is treated as an investigational research compound.

Checking the lab data

A useful certificate confirms the seven-residue sequence by mass spectrometry, with the observed mass matching the theoretical value for Thr-Lys-Pro-Arg-Pro-Gly-Pro, and reports HPLC purity from a dated, batch-numbered run. Because related analogues such as N-acetyl variants are also sold, the report should state plainly whether the peptide is unmodified. The vial should hold a compact white or off-white lyophilized cake with no visible moisture or discoloration.

This listing has an independent lab report attached; the testing panel above summarises what the tested sample contained against its label.

Listing details

Compound

Selank

Synonyms

Tuftsin analogue

Class

Synthetic heptapeptide (tuftsin derivative)

Format

Lyophilized (freeze-dried) powder

Vial strength

5mg

Total content

5 mg

Price per mg

$3.80

Sold by

Imperial Peptides

Ships from

Australia

Lab report

Independent report attached

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 5 mg vial dissolved in 2 mL gives 2.5 mg/mL, or 5 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.