CJC-1295 with DAC 5mg

CJC-1295 with DAC at a glance

Developed by the Canadian company ConjuChem, CJC-1295 is a tetrasubstituted GHRH(1-29) analogue with an extra C-terminal lysine bearing a maleimidopropionic acid group. That group, the Drug Affinity Complex, reacts with a free cysteine on serum albumin after the peptide enters the bloodstream, effectively tethering a small peptide to a large, long-lived carrier protein. Its molecular weight is about 3647 g/mol, considerably heavier than the unconjugated fragment sold as CJC-1295 No DAC.

Price and availability

A single 5mg vial from Imperial Peptides, shipped from Australia. The price is $44.00, or $8.80 per milligram of peptide. 10 brands sell CJC-1295 with DAC on GLP1 Forum Escrow, with a typical price of $2.80–$4.99 per mg (median $3.25); this listing is above the typical range. Your payment waits in escrow until you confirm the parcel arrived, and only then is it released to the brand.

What it is studied for

Pharmacologically, the target is the same GHRH receptor on anterior pituitary somatotrophs that sermorelin and Modified GRF (1-29) activate. What changes is the time course. Once attached to albumin, the peptide escapes rapid renal filtration and enzymatic cleavage, so receptor stimulation is spread over days in published pharmacokinetic studies. Investigators have reported that baseline growth hormone levels rise while some pulsatility is preserved, and that circulating IGF-1 increases in turn. Whether prolonged exposure alters receptor sensitivity over time is one of the questions such studies address.

Research and regulatory status

Early studies in healthy adults described extended elevation of growth hormone and IGF-1 after single and repeated administration. Clinical development was later discontinued, and the compound never progressed to approval. Since then, the literature has stayed small, and much online discussion conflates this molecule with the No-DAC fragment. Anti-doping agencies list it among prohibited GH-releasing factors. Researchers should treat it as an experimental tool with limited long-term data.

Checking the lab data

The deciding measurement is mass: a deconvoluted mass-spectrometry result near 3647 Da confirms the DAC-bearing lysine is present, whereas a value near the mass of Modified GRF (1-29) would indicate the wrong product. The maleimide group is reactive, so degradation products may appear as extra chromatographic peaks; HPLC purity should state its method. Batch number, test date and lab name complete the record. Expect a white lyophilized cake.

An independent lab report is attached to this listing, and the panel above shows the measured result next to the labelled amount.

Listing details

Compound

CJC-1295 with DAC

Synonyms

DAC:GRF, Drug Affinity Complex GHRH

Class

Long-acting GHRH(1-29) analogue

Format

Lyophilized (freeze-dried) powder

Vial strength

5mg

Total content

5 mg

Price per mg

$8.80

Sold by

Imperial Peptides

Ships from

Australia

Lab report

Independent report attached

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 5 mg vial dissolved in 2 mL gives 2.5 mg/mL, or 5 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.