DSIP 10mg

DSIP at a glance

Delta sleep-inducing peptide was isolated by a Swiss research group from the blood of rabbits whose sleep had been induced by electrical stimulation of the brain, and its name reflects that origin. The sequence, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, is short and fully defined. DSIP-like immunoreactivity has since been reported in the brain, pituitary and peripheral tissues, yet a precursor protein or gene has not been clearly identified. Here it is supplied as lyophilized powder for laboratory investigation.

Price and availability

A single 10mg vial from Imperial Peptides, shipped from Australia. At $36.00 for the kit, that works out to $3.60 per mg. 11 brands sell DSIP on GLP1 Forum Escrow, with a typical price of $0.81–$1.10 per mg (median $0.90); this listing is above the typical range. As with every order here, the brand is paid only after you confirm delivery.

What it is studied for

How DSIP acts is still unclear, and that uncertainty runs through the literature. Animal studies variously report shifts in slow-wave sleep, effects on corticotropin and luteinizing-hormone release, modulation of stress responses, and antioxidant activity in tissue preparations. Proposed explanations include interaction with glutamate NMDA receptors, adrenergic signaling or opioid-related pathways, but none has been confirmed as a primary target. Some authors suggest DSIP behaves as a general modulator rather than a dedicated sleep signal, an idea consistent with how variable its sleep effects have been between studies.

Research and regulatory status

Most DSIP research dates from the years following its 1977 discovery and was carried out in rodents, rabbits and isolated tissues, with a handful of small human studies on sleep and withdrawal states that produced inconsistent findings. It never advanced to an approved therapeutic, and newer publications are relatively scarce. Readers should treat older positive reports cautiously, since methods for peptide purity analysis and sleep measurement have changed substantially since that work was done.

Checking the lab data

Since DSIP is a defined nonapeptide, mass spectrometry should confirm a single dominant species matching the calculated mass of the expected sequence; tryptophan oxidation products are worth watching for. HPLC purity should be shown with a chromatogram rather than a bare number, and the report should list peptide content, counter-ion, a white uniform cake, the testing laboratory's name and a batch number that matches the vial label.

This listing has an independent lab report attached; the testing panel above summarises what the tested sample contained against its label.

Listing details

Compound

DSIP

Synonyms

Delta Sleep-Inducing Peptide

Class

Neuropeptide (nonapeptide)

Format

Lyophilized (freeze-dried) powder

Vial strength

10mg

Total content

10 mg

Price per mg

$3.60

Sold by

Imperial Peptides

Ships from

Australia

Lab report

Independent report attached

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 10 mg vial dissolved in 2 mL gives 5 mg/mL, or 10 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.