Name: DSIP
Brand: Lilipeptide
SKU: LILI-dsip
Price: 57.00 USD
Availability: InStock

DSIP at a glance

Delta sleep-inducing peptide was isolated by a Swiss research group from the blood of rabbits whose sleep had been induced by electrical stimulation of the brain, and its name reflects that origin. The sequence, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, is short and fully defined. DSIP-like immunoreactivity has since been reported in the brain, pituitary and peripheral tissues, yet a precursor protein or gene has not been clearly identified. Here it is supplied as lyophilized powder for laboratory investigation.

Price and availability

Sold by Lilipeptide and sent from China, this listing is a listing. It is listed at $57.00. Your payment waits in escrow until you confirm the parcel arrived, and only then is it released to the brand.

This listing: Lilipeptide DSIP

Brand: Lilipeptide
Also sold by: Lab77 Peptides 10mg $50.00 · Imperial Peptides 10mg $36.00 · Uther Peptide 10mg $75.00 · TFC Peptides 10mg $60.00 · Sulan Bio 10mg $90.00 · European Peptide Sciences 10mg $350.00

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

How DSIP acts is still unclear, and that uncertainty runs through the literature. Animal studies variously report shifts in slow-wave sleep, effects on corticotropin and luteinizing-hormone release, modulation of stress responses, and antioxidant activity in tissue preparations. Proposed explanations include interaction with glutamate NMDA receptors, adrenergic signaling or opioid-related pathways, but none has been confirmed as a primary target. Some authors suggest DSIP behaves as a general modulator rather than a dedicated sleep signal, an idea consistent with how variable its sleep effects have been between studies.

Research and regulatory status

Most DSIP research dates from the years following its 1977 discovery and was carried out in rodents, rabbits and isolated tissues, with a handful of small human studies on sleep and withdrawal states that produced inconsistent findings. It never advanced to an approved therapeutic, and newer publications are relatively scarce. Readers should treat older positive reports cautiously, since methods for peptide purity analysis and sleep measurement have changed substantially since that work was done.

Checking the lab data

Since DSIP is a defined nonapeptide, mass spectrometry should confirm a single dominant species matching the calculated mass of the expected sequence; tryptophan oxidation products are worth watching for. HPLC purity should be shown with a chromatogram rather than a bare number, and the report should list peptide content, counter-ion, a white uniform cake, the testing laboratory's name and a batch number that matches the vial label.

This listing has no third-party report on file yet. The lab reports directory and the marketplace show which brands do publish testing.

Listing details

Compound: DSIP
Synonyms: Delta Sleep-Inducing Peptide
Class: Neuropeptide (nonapeptide)
Format: Lyophilized (freeze-dried) powder
Sold by: Lilipeptide
Ships from: China
Lab report: Not yet published

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Buyer questions

Where does the name delta sleep-inducing peptide come from?

Delta refers to the slow, high-amplitude brain waves of deep non-REM sleep. The researchers who isolated the peptide believed it was the factor responsible for transferring that sleep state from one animal to another. Later work showed its effects were neither consistent nor limited to sleep, but the original name stuck.

Why has research interest in DSIP declined?

Without an identified receptor or gene, it was hard to build a clear mechanistic account, and replication of the early sleep findings was uneven. Attention in sleep science shifted toward systems such as orexin and adenosine signaling, which had better-defined molecular targets. DSIP remains of interest mainly as a historical and exploratory research compound.

When does Lilipeptide get paid?

Only after you confirm delivery. Until then the payment is held in escrow, and you can open a claim if anything is wrong with the order.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.