Ipamorelin

Ipamorelin at a glance

Ipamorelin belongs to the growth-hormone secretagogue family and was developed as a smaller, more selective successor to the early GHRP hexapeptides. Its five residues, Aib-His-D-2-Nal-D-Phe-Lys-NH2, include the unnatural amino acid aminoisobutyric acid and two D-configured residues that help it resist proteolysis. The formula is C38H49N9O5, giving a molecular weight of 711.86 g/mol. It is not derived from ghrelin itself; it mimics ghrelin's action at the receptor while sharing none of its sequence.

Price and availability

This is Vital Edge Science‘s listing, dispatched from Australia. It is listed at $49.00. Checkout goes into escrow first; the funds move to Vital Edge Science once delivery is confirmed.

What it is studied for

Ipamorelin is an agonist of GHS-R1a, the receptor through which the stomach hormone ghrelin acts. On pituitary somatotrophs, receptor activation couples to phospholipase C and a rise in intracellular calcium, releasing stored growth hormone; hypothalamic receptors are thought to amplify this by modulating GHRH and somatostatin input. In early animal pharmacology, its release profile was reported to be more selective than that of GHRP-6 or GHRP-2, with little change in ACTH or cortisol even at higher exposures. Effects on appetite appear weaker than those of GHRP-6 in published models, although direct comparisons are limited.

Research and regulatory status

Most ipamorelin data come from rodent and other animal models looking at GH pulsatility, bone mineral content, and gut motility after surgery. A pharmaceutical developer took the compound into mid-stage human trials for postoperative ileus, but that program did not lead to an approved product, so ipamorelin remains a research tool. On GLP1 Forum Escrow it is listed by multiple brands, which makes comparing price per mg alongside each batch's lab report the practical way to judge listings.

Checking the lab data

Identity checks should show a mass spectrum consistent with 711.86 g/mol, with the protonated ion appearing near 712. Because the sequence contains D-residues and Aib, a careful lab may also comment on diastereomeric impurities that a standard HPLC run can miss. The report should give HPLC purity with a chromatogram, net content measured against the stated fill, a white lyophilized cake, and a batch code that matches the vial.

An independent lab report is attached to this listing, and the panel above shows the measured result next to the labelled amount.

Listing details

Compound

Ipamorelin

Class

Selective growth-hormone secretagogue (pentapeptide)

Format

Lyophilized (freeze-dried) powder

Molecular formula

C38H49N9O5

Molecular weight

711.86 g/mol

Sold by

Vital Edge Science

Ships from

Australia

Lab report

Independent report attached

Storage and preparation

Keep unopened freeze-dried vials cold, sealed and out of the light; moisture is what degrades a lyophilized cake fastest. After reconstitution, refrigerate the solution and work within the stability window your protocol sets.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.