Name: Sermorelin
Brand: Lilipeptide
SKU: LILI-sermorelin
Availability: OutOfStock

Sermorelin at a glance

Native growth-hormone-releasing hormone is a 44-residue hypothalamic peptide, yet its first 29 residues carry the receptor-binding activity. Sermorelin is a synthetic copy of that shorter segment, with a listed molecular weight of 3357.9 g/mol and no added half-life extension. That simple design means it is cleared quickly compared with modified analogues such as CJC-1295. Listings are supplied as sermorelin acetate in freeze-dried form, and several brands can be compared per mg on the marketplace.

Price and availability

A listing from Lilipeptide, shipped from China. It is listed at $90.00. Funds stay in escrow and are released to Lilipeptide only when you mark the order as received.

This listing: Lilipeptide Sermorelin

Brand: Lilipeptide
Also sold by: Lab77 Peptides 10mg $63.00 · Kensington Biosciences 10mg $290.00 · European Peptide Sciences 10mg $500.00 · Cyprus Peptides 1mg $176.00 · Peptide Express 5mg $36.00 · Cyprus Peptides 5mg $97.00

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

The peptide binds the GHRH receptor on somatotrophs, the growth-hormone-producing cells of the anterior pituitary. Receptor activation raises cyclic AMP inside those cells, which drives both production and release of stored growth hormone. Circulating GH then prompts the liver to make IGF-1. Because sermorelin works upstream of the pituitary rather than supplying hormone directly, the output stays under the control of somatostatin and of negative feedback from IGF-1, which researchers see as a way to study the axis with its regulatory brakes intact.

Research and regulatory status

Sermorelin has a genuine clinical history. It was approved in the United States for evaluating and treating growth hormone deficiency in children and was later discontinued commercially by its manufacturer. Current research looks at age-related changes in GH secretion, body composition and sleep, mostly in small studies. Research-grade sermorelin listed on the marketplace is not an approved medicine and is not equivalent to any pharmaceutical product.

Checking the lab data

A solid sermorelin report includes a mass spectrometry result matching the expected 3357.9 g/mol for the 29-residue chain, which helps rule out truncated sequences or mislabeled GHRH analogues such as Mod GRF 1-29, whose substitutions shift the mass. HPLC purity should be shown with its chromatogram, together with the measured peptide content per vial. The freeze-dried cake should be white and intact, and the batch number should match the listing.

This listing has no third-party report on file yet. The lab reports directory and the Sermorelin page show which brands do publish testing.

Listing details

Compound: Sermorelin
Synonyms: Sermorelin Acetate, GHRH(1-29)
Class: Growth-hormone-releasing hormone analogue (29-amino-acid fragment)
Format: Lyophilized (freeze-dried) powder
Molecular formula: C₁₄₉H₂₄₆N₄₄O₄₂S
Molecular weight: 3357.9 g/mol
Sold by: Lilipeptide
Ships from: China
Lab report: Not yet published

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Buyer questions

What does the acetate in sermorelin acetate refer to?

Synthetic peptides are usually isolated as salts, and acetate is the counter-ion that pairs with the peptide's basic groups after purification. The salt adds weight to the powder in a vial, which is why reports that state net peptide content, rather than total powder weight, give a more accurate picture of what a vial holds.

Why is sermorelin cleared so quickly?

Unmodified GHRH fragments are rapidly cut by the enzyme dipeptidyl peptidase-4 and other proteases in the blood. Sermorelin carries none of the amino-acid substitutions or albumin-binding groups used in later analogues to slow that breakdown, so its activity in pharmacology studies is brief, which suits research focused on short, discrete stimulation of the pituitary.

What if the parcel never arrives?

Open a claim from your order page. The payment is still in escrow at that point, so a claim decided in your favour is refunded to your Escrow Wallet.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.