Mazdutide 10mg (10 Vials / Kit)

Mazdutide at a glance

Mazdutide is a synthetic peptide whose design traces to oxyntomodulin, a gut hormone that naturally activates both the GLP-1 and glucagon receptors. Eli Lilly discovered it under the code LY3305677 and licensed development in China to Innovent Biologics, where it carries the code IBI362. Sequence modifications and a fatty-acid side chain extend its persistence in circulation well beyond that of the native hormone. Research material is supplied as a white lyophilized powder.

Price and availability

This is TFC Peptides‘s kit of 10 vials at 10mg each (100 mg in total), dispatched from Tianjin, China. $185.00 buys the whole kit, which is $1.85/mg. 3 brands sell Mazdutide on GLP1 Forum Escrow, with a typical price of $1.85–$1.89 per mg (median $1.89); this listing is inside that range. As with every order here, the brand is paid only after you confirm delivery.

What it is studied for

At the GLP-1 receptor, signaling is associated with glucose-dependent insulin secretion, slower gastric emptying and reduced food intake through central pathways. At the glucagon receptor, the picture differs: activation promotes hepatic glucose output but has also been linked to higher energy expenditure, greater hepatic fat oxidation and changes in amino-acid metabolism. The working hypothesis behind dual agonism is that GLP-1 activity offsets glucagon's glucose-raising tendency while the glucagon arm adds liver and energy-expenditure effects. The relative balance between the two receptors is a key design parameter compared across this class.

Research and regulatory status

Innovent has run a series of clinical trials in Chinese adults with obesity or type 2 diabetes, including late-stage studies, and Chinese regulators have approved mazdutide for chronic weight management. Lilly has studied it in separate programs. Outside China, it remains investigational, and regulatory status differs by market, so researchers should check current records for their own jurisdiction. Liver-fat imaging endpoints are a recurring feature of the trial literature.

Checking the lab data

For a lipidated dual agonist, high-resolution mass spectrometry should show a deconvoluted mass consistent with the full peptide plus its fatty-acid side chain; a lighter result suggests a missing modification or a different molecule. HPLC purity should be reported with the chromatogram, batch number and test date. Since several incretin-class peptides look identical as powders, identity testing matters more than appearance. Expect a white lyophilized cake.

This listing has no third-party report on file yet. The lab reports directory and the marketplace show which brands do publish testing.

Listing details

Compound

Mazdutide

Synonyms

LY3305677, IBI362

Class

Dual GLP-1 / glucagon receptor agonist

Format

Lyophilized (freeze-dried) powder

Vial strength

10mg

Vials per kit

10

Total content

100 mg

Price per mg

$1.85

Sold by

TFC Peptides

Ships from

Tianjin, China

Lab report

Not yet published

Storage and preparation

Keep unopened freeze-dried vials cold, sealed and out of the light; moisture is what degrades a lyophilized cake fastest. After reconstitution, refrigerate the solution and work within the stability window your protocol sets.

Concentration arithmetic: one 10 mg vial dissolved in 2 mL gives 5 mg/mL, or 10 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.