5-Amino-1MQ 50mg (10 Vials / Kit)

5-Amino-1MQ at a glance

5-Amino-1-methylquinolinium is a small aromatic cation rather than a chain of amino acids, even though it is sold alongside peptides. It emerged from structure-activity work on quinolinium analogues aimed at blocking nicotinamide N-methyltransferase, or NNMT, while still crossing cell membranes. NNMT expression is comparatively high in liver and adipose tissue. The material is offered as a freeze-dried powder for laboratory study; as a small molecule it has no amino-acid sequence, whatever a product template may suggest.

Price and availability

SynTide Research lists this kit of 10 vials at 50mg each (500 mg in total), shipped from China. The price is $122.41, or $0.245 per milligram of peptide. Across 7 brands listing 5-Amino-1MQ here, the middle half of prices falls between $0.245 and $0.81 per mg; this kit is inside that range. Checkout goes into escrow first; the funds move to SynTide Research once delivery is confirmed.

What it is studied for

NNMT transfers a methyl group from S-adenosylmethionine to nicotinamide, producing 1-methylnicotinamide. Inhibiting the enzyme is hypothesized to do two things at once: preserve nicotinamide for the NAD+ salvage pathway and spare the cell's methyl-donor pool. In mouse adipocyte and diet-induced obesity experiments, 5-amino-1MQ has been associated with higher intracellular NAD+ and reduced lipogenesis, while studies in aged mice explored muscle stem-cell activity. Which downstream pathways, such as sirtuin signaling, account for these observations is still being worked out, and selectivity against related methyltransferases continues to be characterized.

Research and regulatory status

Published research on 5-amino-1MQ is limited to cell culture and rodent models, mainly from a small number of academic groups. There are no completed controlled human trials, and the compound is not an approved medicine. That makes it an early-stage tool compound. Readers should be wary of marketing claims that go beyond the preclinical data, and should judge each GLP1 Forum Escrow listing by the batch-specific lab report attached to it rather than by descriptive copy.

Checking the lab data

Because this is a small molecule, identity is best confirmed by mass spectrometry showing the quinolinium cation, ideally supported by NMR or UV spectra. The report should state which salt form is supplied, for example iodide, since the counter-ion changes the amount of active cation per milligram. HPLC purity with a chromatogram, residual solvent screening and appearance belong on the report; any amino-acid sequence or peptide-content claim would suggest a copied template.

No independent report is attached to this listing yet. You can compare brands that publish one on the marketplace or browse the lab reports directory.

Listing details

Compound

5-Amino-1MQ

Synonyms

5-Amino-1-Methylquinolinium

Class

Small-molecule NNMT inhibitor

Format

Lyophilized (freeze-dried) powder

Vial strength

50mg

Vials per kit

10

Total content

500 mg

Price per mg

$0.245

Sold by

SynTide Research

Ships from

China

Lab report

Not yet published

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 50 mg vial dissolved in 2 mL gives 25 mg/mL, or 50 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.