Mod GRF 1-29 (CJC-1295 no DAC) 5mg

CJC-1295 No DAC at a glance

Native growth hormone-releasing hormone is a longer peptide, but its N-terminal 29 residues carry the biological activity; sermorelin is that fragment left unmodified. Modified GRF (1-29), sold widely as CJC-1295 No DAC, replaces four of those residues to resist cleavage by dipeptidyl peptidase-4 and to limit oxidation and rearrangement. The name is a market convention: the original CJC-1295 described in the scientific literature included the albumin-binding DAC group, which this version omits entirely.

Price and availability

Peptide Express lists this single 5mg vial, shipped from the United States. At $39.00 for the kit, that works out to $7.80 per mg. 16 brands sell CJC-1295 No DAC on GLP1 Forum Escrow, with a typical price of $1.40–$4.29 per mg (median $1.70); this listing is above the typical range. Checkout goes into escrow first; the funds move to Peptide Express once delivery is confirmed.

What it is studied for

The peptide acts as an agonist at the GHRH receptor on somatotroph cells of the anterior pituitary. Receptor activation raises intracellular cyclic AMP, promoting both growth hormone synthesis and release of stored hormone. Because the molecule is cleared fairly quickly, its effect is described as a discrete burst that sits within the body's own rhythm and remains subject to inhibition by somatostatin. That feedback-sensitive profile is why researchers pair it with ghrelin-receptor agonists, whose separate pathway can be examined alongside GHRH signaling, and why it is contrasted with long-acting analogues that produce more continuous exposure.

Research and regulatory status

Published human data on this exact sequence are thin. Much of what circulates about it is extrapolated from studies of sermorelin, tesamorelin and the DAC-bearing CJC-1295, or from animal endocrinology. It has never been approved as a medicine anywhere, and anti-doping rules prohibit it within the growth-hormone-releasing-factor category. Researchers should therefore treat the compound as an experimental tool and read secondary claims about body composition with caution.

Checking the lab data

Mass spectrometry should match the theoretical mass of Modified GRF (1-29) and, importantly, should not show the higher mass of the DAC conjugate, which is the most common mix-up in this category. HPLC purity should be accompanied by the batch number, test date and laboratory name. Labels that say only CJC-1295 are ambiguous, so the report is the deciding document. Expect a white lyophilized cake.

This listing has no third-party report on file yet. The lab reports directory and the CJC-1295 No DAC page show which brands do publish testing.

Listing details

Compound

CJC-1295 No DAC

Synonyms

Modified GRF (1-29), Mod GRF 1-29, Tetrasubstituted GHRH(1-29)

Class

Growth hormone-releasing hormone (GHRH) analogue

Format

Lyophilized (freeze-dried) powder

Vial strength

5mg

Total content

5 mg

Price per mg

$7.80

Sold by

Peptide Express

Ships from

United States

Lab report

Not yet published

Storage and preparation

Keep unopened freeze-dried vials cold, sealed and out of the light; moisture is what degrades a lyophilized cake fastest. After reconstitution, refrigerate the solution and work within the stability window your protocol sets.

Concentration arithmetic: one 5 mg vial dissolved in 2 mL gives 2.5 mg/mL, or 5 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.