Name: Snap-8
Brand: Lilipeptide
SKU: LILI-snap-8
Price: 57.00 USD
Availability: InStock

Snap-8 at a glance

Known by its cosmetic ingredient name acetyl octapeptide-3, Snap-8 was built by lengthening the Argireline hexapeptide with two more amino acids at the C-terminal end. Both sequences are modeled on the N-terminal portion of SNAP-25, a protein that nerve endings use to release neurotransmitters. Snap-8 belongs to the cosmetic-peptide category, studied in skin-care formulation science rather than in hormone or metabolic research, and it is offered as freeze-dried powder.

Price and availability

A listing from Lilipeptide, shipped from China. It is listed at $57.00. As with every order here, the brand is paid only after you confirm delivery.

This listing: Lilipeptide Snap-8

Brand: Lilipeptide
Also sold by: Uther Peptide 10mg $40.00 · HK Peptide 10mg $40.00 · TFC Peptides 10mg $40.00 · SSRBIO 10mg $40.05 · Jinlu Peptides 10mg $112.50 · Uther Peptide Snap-8 Raw Powder 1g for external $105.00

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

Muscle contraction depends on nerve endings releasing acetylcholine, and that release requires the SNARE complex, a set of proteins including SNAP-25 that fuse vesicles with the cell membrane. Snap-8 is designed to resemble part of SNAP-25 and is proposed to compete for its place in the complex, making the assembly less efficient. In cell assays and cosmetic studies, this has been linked to reduced neurotransmitter release and to measurements of expression-line depth in topical formulations. The size of these effects, and how much peptide penetrates skin, remain debated.

Research and regulatory status

Research sits in dermatology and cosmetic science. Published and manufacturer studies use in vitro assays and topical formulations applied to the forehead or around the eyes, and many are small or industry-sponsored. Snap-8 is used as a cosmetic ingredient rather than regulated as a drug, and it has no approved medical use. It is often evaluated alongside Argireline and other SNARE-targeting peptides as comparators.

Checking the lab data

A credible report shows a mass spectrometry result matching the acetylated, amidated eight-residue sequence, which distinguishes Snap-8 from Argireline, the shorter hexapeptide with a lower mass. HPLC purity with the chromatogram and measured content are standard. For raw-powder listings intended for formulation work, a description of appearance and moisture content is useful, and the report should state whether the material is the free peptide or an acetate salt.

This listing has no third-party report on file yet. The lab reports directory and the marketplace show which brands do publish testing.

Listing details

Compound: Snap-8
Synonyms: Acetyl Octapeptide-3
Class: Cosmetic peptide (SNARE-complex modulator)
Format: Lyophilized (freeze-dried) powder
Sold by: Lilipeptide
Ships from: China
Lab report: Not yet published

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Buyer questions

What is the SNARE complex?

It is a group of proteins, including SNAP-25, syntaxin and synaptobrevin, that pull a neurotransmitter-filled vesicle against the nerve-cell membrane so the two can fuse and release their contents. Because the complex is essential for acetylcholine release at nerve-muscle junctions, peptides that interfere with its assembly are studied in cosmetic science.

What does acetyl octapeptide-3 mean?

It is the INCI name, the standardized label used on cosmetic ingredient lists. Acetyl indicates a capping group on the N-terminus, octapeptide means eight amino acids, and the final number distinguishes it from other octapeptides in the naming system. Seeing this name on a label points to Snap-8 rather than Argireline.

When does Lilipeptide get paid?

Only after you confirm delivery. Until then the payment is held in escrow, and you can open a claim if anything is wrong with the order.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.