AOD-9604 5mg (10 Vials / Kit)

AOD-9604 at a glance

AOD-9604 takes the tail end of human growth hormone, the region spanning residues 176 to 191, and carries a tyrosine at the start of the chain to improve stability. It was developed by researchers in Australia who wanted to keep the portion of GH associated with fat metabolism while leaving out the regions that drive tissue growth and raise IGF-1. The result is a short peptide, also sold as hGH Fragment 176-191, supplied here as freeze-dried powder.

Price and availability

A kit of 10 vials at 5mg each (50 mg in total) from Lianhua Peptide Co., shipped from Hangzhou, China. $95.11 buys the whole kit, which is $1.90/mg. 14 brands sell AOD-9604 on GLP1 Forum Escrow, with a typical price of $1.90–$3.50 per mg (median $1.90); this listing is inside that range. Checkout goes into escrow first; the funds move to Lianhua Peptide Co. once delivery is confirmed.

What it is studied for

Studies in fat cells and in rodents suggest the fragment stimulates lipolysis, the breakdown of stored triglycerides, and suppresses lipogenesis, the formation of new fat, in ways that resemble full-length growth hormone. What distinguishes it in that research is the absence of the receptor activity responsible for raising IGF-1 or affecting blood glucose. Involvement of beta-3 adrenergic receptors has been proposed in some animal work, though the exact pathway has not been fully established. Separately, investigators have looked at possible effects on cartilage in joint-injury models.

Research and regulatory status

Most data come from rodent and cell-culture studies. Human trials were run for obesity during clinical development, and the published results did not show enough effect for the program to continue toward approval. AOD-9604 is not an approved medicine anywhere, and the World Anti-Doping Agency treats it as a prohibited substance. Joint and cartilage research is early and small in scale, so the overall evidence base remains thin.

Checking the lab data

For AOD-9604, a good report gives a mass spectrometry result consistent with the expected sequence, including the N-terminal tyrosine. The chain contains a pair of cysteines that normally form a disulfide bond, so the measured mass should correspond to the expected oxidized form rather than the open chain. Look for HPLC purity with a chromatogram, measured content per vial and a white, intact freeze-dried cake, plus the lab name and batch number.

This listing has no third-party report on file yet. The lab reports directory and the AOD-9604 page show which brands do publish testing.

Listing details

Compound

AOD-9604

Synonyms

hGH Fragment 176-191, Anti-Obesity Drug 9604

Class

Modified growth-hormone fragment peptide

Format

Lyophilized (freeze-dried) powder

Vial strength

5mg

Vials per kit

10

Total content

50 mg

Price per mg

$1.90

Sold by

Lianhua Peptide Co.

Ships from

Hangzhou, China

Lab report

Not yet published

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 5 mg vial dissolved in 2 mL gives 2.5 mg/mL, or 5 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.