Argireline 10mg (30 Vials / Kit)

Argireline at a glance

Argireline is the trade name for an acetylated hexapeptide, Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2, developed by the Spanish ingredient company Lipotec for skin-care formulations. Its sequence copies the N-terminal end of SNAP-25, a nerve-terminal protein involved in neurotransmitter release. On cosmetic labels it appears as acetyl hexapeptide-3 or, under a later naming update, acetyl hexapeptide-8. It is also the parent sequence from which the longer Snap-8 octapeptide was derived.

Price and availability

This is Jinlu Peptides‘s kit of 30 vials at 10mg each (300 mg in total), dispatched from China. $270.00 buys the whole kit, which is $0.90/mg. 2 brands currently sell Argireline here, so compare their listings before ordering. As with every order here, the brand is paid only after you confirm delivery.

What it is studied for

Release of acetylcholine at nerve-muscle junctions depends on the SNARE complex, a bundle of proteins including SNAP-25, syntaxin and synaptobrevin that drives vesicle fusion. Argireline is proposed to compete with SNAP-25 for a place in that complex, destabilizing its assembly and reducing neurotransmitter release in cell-based assays. Cosmetic research uses that mechanism to study expression lines in topical formulations. How much of the peptide crosses the skin barrier, and how large any effect is, remain subjects of debate.

Research and regulatory status

Studies are concentrated in cosmetic science and dermatology, using in vitro assays and small topical trials, several of them sponsored by ingredient makers. Argireline is regulated as a cosmetic ingredient rather than a drug and has no approved medical use. It is often used as a reference compound when newer SNARE-targeting peptides, such as Snap-8, are evaluated. Large independent controlled studies are limited.

Checking the lab data

A credible report should confirm the acetylated, amidated hexapeptide by mass spectrometry and give HPLC purity with its chromatogram. The mass separates Argireline from Snap-8, which is two residues longer. Because the sequence includes methionine, oxidation can appear as a small mass shift worth checking. Measured content, a description of the white powder, the salt form and a batch number linked to the listing should also be documented.

This listing has no third-party report on file yet. The lab reports directory and the marketplace show which brands do publish testing.

Listing details

Compound

Argireline

Vial strength

10mg

Vials per kit

30

Total content

300 mg

Price per mg

$0.90

Sold by

Jinlu Peptides

Ships from

China

Lab report

Not yet published

Storage and preparation

Keep unopened freeze-dried vials cold, sealed and out of the light; moisture is what degrades a lyophilized cake fastest. After reconstitution, refrigerate the solution and work within the stability window your protocol sets.

Concentration arithmetic: one 10 mg vial dissolved in 2 mL gives 5 mg/mL, or 10 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.