Name: KPV 5mg (10 Vials / Kit)
Brand: HK Peptide
SKU: HK-KPV5
Price: 35.00 USD
Availability: InStock

KPV at a glance

KPV is three amino acids long: lysine, proline and valine, matching positions 11 to 13 at the carboxyl end of alpha-melanocyte-stimulating hormone. Alpha-MSH is cleaved from the larger precursor pro-opiomelanocortin, and early work found that this terminal fragment kept a portion of the hormone's anti-inflammatory activity. Its small size makes it simple to synthesize and characterize. Listings here supply KPV as a freeze-dried powder, and it also appears as one component of certain multi-peptide blends in the catalogue.

Price and availability

A kit of 10 vials at 5mg each (50 mg in total) from HK Peptide, shipped from Hong Kong, Hong Kong. The price is $35.00, or $0.70 per milligram of peptide. Across 16 brands listing KPV here, the middle half of prices falls between $0.55 and $3.80 per mg; this kit is inside that range. Your payment waits in escrow until you confirm the parcel arrived, and only then is it released to the brand.

This listing: HK Peptide KPV

Brand: HK Peptide
Kit: 10 vials × 5 mg (50 mg in total)
Price per vial: $3.50
Price per mg: $0.70
Other strengths: 10mg $55.00
Also sold by: Vital Edge Science KPV $32.00 · Peptide Express 10mg $50.00 · Cyprus Peptides 10mg $97.00 · Lab77 Peptides 10mg $42.00 · Imperial Peptides 10mg $38.00 · Uther Peptide 10mg $80.00

Lab testing

HK Peptide published a Janoshik #121855 report for this compound. Test: Purity & Content (HPLC). Result: 99.23% purity · 12.88 mg. Tested Mar 16, 2026. The vial tested was a different strength than this listing, so treat it as evidence for the compound and ask for the batch COA for this exact strength. Verification key 5VZXZD8NAF97 can be checked at janoshik.com.

View the report · How to read it (Testing 101) · Every report for this compound

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

How much KPV depends on melanocortin receptors is unsettled, but pigment effects are not expected from such a short fragment. A leading proposal is that the proton-coupled di- and tripeptide transporter PepT1 carries it into epithelial and immune cells, where it interferes with NF-kB activation and lowers pro-inflammatory cytokine output in cell models. Some reports also describe antimicrobial effects. Nanoparticle and hydrogel formulations have been used in mouse colitis experiments to concentrate the peptide in inflamed intestinal tissue, though whether intracellular action explains all of its reported activity remains debated.

Research and regulatory status

Published work is preclinical: cultured intestinal epithelial cells, macrophage assays, keratinocyte and wound models, and chemically induced colitis in mice. Several groups have tested delivery systems to improve local exposure. No registered human clinical trial has established effects, and KPV is not an approved medicine anywhere we are aware of. Because uptake appears to depend on transporter expression, findings in one tissue may not carry over to another, a caution worth keeping in mind when reading summaries of this literature.

Checking the lab data

With only three residues, KPV gives a simple mass spectrum, so the observed mass should sit close to the calculated value for Lys-Pro-Val without stray peaks from protecting groups or truncated dipeptides. HPLC purity needs a visible chromatogram, because small hydrophilic peptides can elute early and hide impurities near the solvent front. The report should also note the counter-ion form, such as acetate, along with peptide content, a white lyophilized appearance and batch traceability.

An independent lab report is attached to this listing, and the panel above shows the measured result next to the labelled amount.

Listing details

Compound: KPV
Synonyms: Lys-Pro-Val, alpha-MSH(11-13)
Class: Naturally occurring tripeptide, C-terminal alpha-MSH fragment
Format: Lyophilized (freeze-dried) powder
Vial strength: 5mg
Vials per kit: 10
Total content: 50 mg
Price per mg: $0.70
Sold by: HK Peptide
Ships from: Hong Kong, Hong Kong
Lab report: Independent report attached

Storage and preparation

Keep unopened freeze-dried vials cold, sealed and out of the light; moisture is what degrades a lyophilized cake fastest. After reconstitution, refrigerate the solution and work within the stability window your protocol sets.

Concentration arithmetic: one 5 mg vial dissolved in 2 mL gives 2.5 mg/mL, or 5 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Why is KPV so often discussed in gut research?

The PepT1 transporter proposed to carry KPV into cells is abundant in the intestinal lining and has been reported to increase in inflamed colon tissue in some models. That expression pattern made the gut a natural place to test the tripeptide, and most of the stronger preclinical data come from mouse colitis experiments.

Why does KPV appear in blends such as Coremend?

Blend makers pair KPV with repair-focused peptides like BPC-157 and TB-500 so researchers can examine inflammatory signaling and tissue remodeling within a single model. The pairing is a product decision rather than a tested formulation; evidence for KPV comes from studies of the tripeptide on its own, not from the fixed blends.

How much KPV is in this listing?

10 vials of 5mg each — 50 mg in all. Where a lab report exists, the testing panel above shows what the brand's tested sample actually measured.

When does HK Peptide get paid?

Only after you confirm delivery. Until then the payment is held in escrow, and you can open a claim if anything is wrong with the order.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.