Name: Epithalon 50mg (10 Vials / Kit)
Brand: HK Peptide
SKU: HK-ET50
Price: 100.00 USD
Availability: InStock

Epitalon at a glance

Epitalon is a tetrapeptide with the sequence Ala-Glu-Asp-Gly, formula C14H22N4O9 and a molecular weight of 390.35 g/mol. Vladimir Khavinson's group in St. Petersburg synthesized it after analyzing the amino-acid composition of epithalamin, a pineal gland extract the group had been testing, intending a reproducible, chemically defined successor. Its small size makes it inexpensive to synthesize and simple to characterize, and it is among the most frequently listed of the bioregulator peptides.

Price and availability

A kit of 10 vials at 50mg each (500 mg in total) from HK Peptide, shipped from Hong Kong, Hong Kong. $100.00 buys the whole kit, which is $0.20/mg. Of the 18 Epitalon listings on the marketplace, from 14 brands, this is the lowest price per mg. Checkout goes into escrow first; the funds move to HK Peptide once delivery is confirmed.

This listing: HK Peptide Epitalon

Brand: HK Peptide
Kit: 10 vials × 50 mg (500 mg in total)
Price per vial: $10.00
Price per mg: $0.20
Other strengths: 10mg $25.00
Also sold by: Cyprus Peptides 50mg $116.00 · Uther Peptide 50mg $240.00 · Imperial Peptides 10mg $25.00 · Peptide Express 10mg $33.00 · Uther Peptide 10mg $60.00 · SSRBIO 10mg $48.60

Lab testing

HK Peptide published a Janoshik #121852 report for this compound. Test: Purity & Content (HPLC). Result: 99.49% purity · 62.39 mg. Tested Mar 16, 2026. Verification key NT378RPTI66C can be checked at janoshik.com.

View the report · How to read it (Testing 101) · Every report for this compound

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

The most cited claim concerns telomerase. Work in cultured human fibroblasts and other cells reported increased expression of the catalytic telomerase subunit and longer telomeres after exposure, findings that have drawn attention but limited replication. A second thread involves the pineal gland: studies in aging animals describe restored nocturnal melatonin rhythms. The originating group also proposes that short peptides bind specific DNA sequences or histone proteins, altering chromatin accessibility and gene transcription. Changes in antioxidant enzymes have been reported too. Each of these is a hypothesis under investigation rather than a settled mechanism.

Research and regulatory status

Most studies were produced by the St. Petersburg Institute of Bioregulation and Gerontology and its collaborators: cell culture, rodent and fruit-fly lifespan experiments, and small human studies in older adults. Methodological detail in some of these papers is sparse, and large independent trials are absent. Epitalon is not approved as a medicine in the United States or the EU. Readers should weigh the literature as early-stage and concentrated within one research network.

Checking the lab data

With only four residues, Epitalon is easy to characterize but also easy to substitute. A credible report shows a mass-spectrometry result matching Ala-Glu-Asp-Gly, an HPLC chromatogram with the main peak clearly resolved and its purity stated, and a batch number tied to the vial. Look for a small, white, dense lyophilized cake. Results from an independent third-party lab carry more weight than a manufacturer's in-house sheet.

This listing has an independent lab report attached; the testing panel above summarises what the tested sample contained against its label.

Listing details

Compound: Epitalon
Synonyms: Epithalon, Epithalamin fragment
Class: Synthetic tetrapeptide bioregulator (Ala-Glu-Asp-Gly)
Format: Lyophilized (freeze-dried) powder
Molecular formula: C14H22N4O9
Molecular weight: 390.35 g/mol
Vial strength: 50mg
Vials per kit: 10
Total content: 500 mg
Price per mg: $0.20
Sold by: HK Peptide
Ships from: Hong Kong, Hong Kong
Lab report: Independent report attached

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 50 mg vial dissolved in 2 mL gives 25 mg/mL, or 50 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Why is Epitalon spelled several different ways?

Transliteration from Russian produced Epitalon, Epithalon and occasionally Epithalone, and some sellers use AEDG after its one-letter sequence. These all describe the same tetrapeptide. Searching each spelling helps when gathering literature, and checking the sequence on the analytical report confirms that the vial matches the name.

Has Epitalon's telomerase effect been independently confirmed?

Only partially. Most reports come from the originating group or its close collaborators, and independent laboratories have published relatively few direct replications. Telomere measurements are also technically sensitive to method. Until broader replication appears, the telomerase findings are best viewed as intriguing preliminary results rather than an established property.

How much Epitalon is in this listing?

10 vials of 50mg each — 500 mg in all. Where a lab report exists, the testing panel above shows what the brand's tested sample actually measured.

When does HK Peptide get paid?

Only after you confirm delivery. Until then the payment is held in escrow, and you can open a claim if anything is wrong with the order.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.