Mazdutide 5mg (10 Vials / Kit)

Mazdutide at a glance

Mazdutide is a synthetic peptide whose design traces to oxyntomodulin, a gut hormone that naturally activates both the GLP-1 and glucagon receptors. Eli Lilly discovered it under the code LY3305677 and licensed development in China to Innovent Biologics, where it carries the code IBI362. Sequence modifications and a fatty-acid side chain extend its persistence in circulation well beyond that of the native hormone. Research material is supplied as a white lyophilized powder.

Price and availability

Sold by TFC Peptides and sent from Tianjin, China, this listing is a kit of 10 vials at 5mg each (50 mg in total). At $110.00 for the kit, that works out to $2.20 per mg. Across 3 brands listing Mazdutide here, the middle half of prices falls between $1.85 and $1.89 per mg; this kit is above the typical range. Your payment waits in escrow until you confirm the parcel arrived, and only then is it released to the brand.

What it is studied for

At the GLP-1 receptor, signaling is associated with glucose-dependent insulin secretion, slower gastric emptying and reduced food intake through central pathways. At the glucagon receptor, the picture differs: activation promotes hepatic glucose output but has also been linked to higher energy expenditure, greater hepatic fat oxidation and changes in amino-acid metabolism. The working hypothesis behind dual agonism is that GLP-1 activity offsets glucagon's glucose-raising tendency while the glucagon arm adds liver and energy-expenditure effects. The relative balance between the two receptors is a key design parameter compared across this class.

Research and regulatory status

Innovent has run a series of clinical trials in Chinese adults with obesity or type 2 diabetes, including late-stage studies, and Chinese regulators have approved mazdutide for chronic weight management. Lilly has studied it in separate programs. Outside China, it remains investigational, and regulatory status differs by market, so researchers should check current records for their own jurisdiction. Liver-fat imaging endpoints are a recurring feature of the trial literature.

Checking the lab data

For a lipidated dual agonist, high-resolution mass spectrometry should show a deconvoluted mass consistent with the full peptide plus its fatty-acid side chain; a lighter result suggests a missing modification or a different molecule. HPLC purity should be reported with the chromatogram, batch number and test date. Since several incretin-class peptides look identical as powders, identity testing matters more than appearance. Expect a white lyophilized cake.

No independent report is attached to this listing yet. You can compare brands that publish one on the marketplace or browse the lab reports directory.

Listing details

Compound

Mazdutide

Synonyms

LY3305677, IBI362

Class

Dual GLP-1 / glucagon receptor agonist

Format

Lyophilized (freeze-dried) powder

Vial strength

5mg

Vials per kit

10

Total content

50 mg

Price per mg

$2.20

Sold by

TFC Peptides

Ships from

Tianjin, China

Lab report

Not yet published

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 5 mg vial dissolved in 2 mL gives 2.5 mg/mL, or 5 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.