MGF 2mg (10 Vials / Kit)

MGF (Mechano Growth Factor) at a glance

Mechano Growth Factor is the name Geoffrey Goldspink's group in London gave to an alternatively spliced form of the IGF-1 gene that muscle produces after stretch or damage, known in humans as IGF-1Ec. The splice change gives the precursor a distinct C-terminal E-domain. Most research products labeled MGF are not the full protein but a synthetic peptide matching that unique E-domain region, sometimes with stabilizing amino-acid changes or attached polyethylene glycol, sold as PEG-MGF.

Price and availability

Sold by TFC Peptides and sent from Tianjin, China, this listing is a kit of 10 vials at 2mg each (20 mg in total). At $45.00 for the kit, that works out to $2.25 per mg. Of the 3 MGF (Mechano Growth Factor) listings on the marketplace, from 3 brands, this is the lowest price per mg. Funds stay in escrow and are released to TFC Peptides only when you mark the order as received.

What it is studied for

The original proposal was that the MGF E-peptide acts as a local signal, separate from mature IGF-1, that activates muscle satellite cells and expands the pool of proliferating myoblasts before they fuse into fibers. Some cell studies report effects on myoblast proliferation and survival that persist when the IGF-1 receptor is blocked, implying a different receptor that has not been identified. Other laboratories have found little or no activity for the synthetic E-peptide, and whether it functions independently in living tissue remains disputed.

Research and regulatory status

MGF research consists of cell culture and animal studies of muscle, heart, bone and neural tissue, plus human biopsy studies measuring IGF-1Ec gene expression after exercise. Those expression studies describe the natural splice variant rather than testing the synthetic peptide. No clinical trials of MGF peptides have been published, they are not approved medicines, and mechano growth factors are named on the World Anti-Doping Agency's prohibited list.

Checking the lab data

Because the term MGF covers several different products, the report should state the exact sequence tested, including any substitutions, and whether PEG is attached. Mass spectrometry should match the calculated mass for that sequence; for PEGylated material, a broad mass distribution is normal and should be described. HPLC purity needs a chromatogram. The lyophilized cake should be white and uniform.

No independent report is attached to this listing yet. You can compare brands that publish one on the marketplace or browse the lab reports directory.

Listing details

Compound

MGF (Mechano Growth Factor)

Vial strength

2mg

Vials per kit

10

Total content

20 mg

Price per mg

$2.25

Sold by

TFC Peptides

Ships from

Tianjin, China

Lab report

Not yet published

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 2 mg vial dissolved in 2 mL gives 1 mg/mL, or 2 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.