Name: Melanotan 1 10mg (10 Vials / Kit)
Brand: HK Peptide
SKU: HK-MT1
Price: 50.00 USD
Availability: InStock

Melanotan 1 at a glance

Melanotan 1 is a linear 13-amino-acid analogue of alpha-MSH developed at the University of Arizona. Two substitutions in the native sequence matter: norleucine replaces an oxidation-prone methionine, and D-phenylalanine replaces L-phenylalanine, increasing potency and resistance to enzymes. Its formula is C78H111N21O19 and its molecular weight 1646.8 g/mol. The international nonproprietary name for the same molecule is afamelanotide. Listings here are lyophilized research material, distinct from the regulated clinical implant.

Price and availability

Sold by HK Peptide and sent from Hong Kong, Hong Kong, this listing is a kit of 10 vials at 10mg each (100 mg in total). At $50.00 for the kit, that works out to $0.50 per mg. 8 brands sell Melanotan 1 on GLP1 Forum Escrow, with a typical price of $0.479–$0.80 per mg (median $0.60); this listing is inside that range. As with every order here, the brand is paid only after you confirm delivery.

This listing: HK Peptide Melanotan 1

Brand: HK Peptide
Kit: 10 vials × 10 mg (100 mg in total)
Price per vial: $5.00
Price per mg: $0.50
Also sold by: TFC Peptides 10mg $45.00 · Cyprus Peptides 10mg $152.00 · Lab77 Peptides 10mg $50.00 · Sulan Bio 10mg $80.00 · Uther Peptide 10mg $60.00 · Lilipeptide Melanotan 1 $68.00

Lab testing

HK Peptide published a Janoshik #114470 report for this compound. Test: Purity & Content (HPLC). Result: 99.42% purity · 10.04 mg. Tested Mar 12, 2026. Verification key SQU5EW4IBRAU can be checked at janoshik.com.

View the report · How to read it (Testing 101) · Every report for this compound

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

The peptide is a potent agonist at the melanocortin-1 receptor on melanocytes. MC1R couples to Gs, so activation raises cAMP and switches on MITF-driven transcription of tyrosinase and related enzymes, steering melanocytes toward brown-black eumelanin instead of red-yellow pheomelanin. It also has lower but measurable activity at other melanocortin receptors. Research additionally examines whether MC1R signaling contributes to DNA-repair and antioxidant responses in skin cells beyond pigment production itself, a line of inquiry that remains under investigation.

Research and regulatory status

Afamelanotide has a regulated clinical record: controlled trials in erythropoietic protoporphyria supported approval in Europe and later in the United States, where the approved product is a dissolving implant used under medical supervision. Investigators have also studied it in vitiligo, polymorphic light eruption and other photodermatoses, with varying results. Research-grade Melanotan 1 is not that product. On GLP1 Forum Escrow it is listed for laboratory study, and its quality depends on each brand's synthesis and testing.

Checking the lab data

Identity should be confirmed by mass spectrometry consistent with 1646.8 g/mol, which also separates it from Melanotan 2, a smaller cyclic analogue with a very different mass. HPLC purity should be supported by a chromatogram and a stated method. The report should include peptide content per vial, the appearance of a white lyophilized cake, a batch number matching the label, and the name of the independent laboratory that ran the tests.

An independent lab report is attached to this listing, and the panel above shows the measured result next to the labelled amount.

Listing details

Compound: Melanotan 1
Synonyms: Afamelanotide
Class: Synthetic alpha-MSH analogue (13-amino-acid peptide)
Format: Lyophilized (freeze-dried) powder
Molecular formula: C78H111N21O19
Molecular weight: 1646.8 g/mol
Vial strength: 10mg
Vials per kit: 10
Total content: 100 mg
Price per mg: $0.50
Sold by: HK Peptide
Ships from: Hong Kong, Hong Kong
Lab report: Independent report attached

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 10 mg vial dissolved in 2 mL gives 5 mg/mL, or 10 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Why was norleucine substituted into the sequence?

Native alpha-MSH contains methionine, which oxidizes easily and can lose activity during storage or in biological fluids. Norleucine has a similar side-chain length without the sulfur atom, so it keeps the shape the receptor recognizes while removing that weak point. This kind of substitution is a common strategy in peptide design.

Is Melanotan 1 studied only for tanning?

No. Pigmentation is the most visible outcome, but research also covers photoprotection in light-sensitivity disorders, vitiligo repigmentation and the broader biology of melanocortin signaling in skin. Much of the human data comes from clinical work on afamelanotide rather than research-grade material, so the two should be kept distinct when reading studies.

How much Melanotan 1 is in this listing?

10 vials of 10mg each — 100 mg in all. Where a lab report exists, the testing panel above shows what the brand's tested sample actually measured.

When does HK Peptide get paid?

Only after you confirm delivery. Until then the payment is held in escrow, and you can open a claim if anything is wrong with the order.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.