Name: 5-Amino-1MQ 50mg (10 Vials / Kit)
Brand: SynTide Research
SKU: ST-5AMQ
Price: 122.41 USD
Availability: InStock

5-Amino-1MQ at a glance

5-Amino-1-methylquinolinium is a small aromatic cation rather than a chain of amino acids, even though it is sold alongside peptides. It emerged from structure-activity work on quinolinium analogues aimed at blocking nicotinamide N-methyltransferase, or NNMT, while still crossing cell membranes. NNMT expression is comparatively high in liver and adipose tissue. The material is offered as a freeze-dried powder for laboratory study; as a small molecule it has no amino-acid sequence, whatever a product template may suggest.

Price and availability

SynTide Research lists this kit of 10 vials at 50mg each (500 mg in total), shipped from China. The price is $122.41, or $0.245 per milligram of peptide. Across 7 brands listing 5-Amino-1MQ here, the middle half of prices falls between $0.245 and $0.81 per mg; this kit is inside that range. Checkout goes into escrow first; the funds move to SynTide Research once delivery is confirmed.

This listing: SynTide Research 5-Amino-1MQ

Brand: SynTide Research
Kit: 10 vials × 50 mg (500 mg in total)
Price per vial: $12.24
Price per mg: $0.24
Also sold by: TFC Peptides 50mg $75.00 · HK Peptide 50mg $100.00 · Uther Peptide 50mg $195.00 · Lilipeptide 5-amino-1mq $90.00 · Uther Peptide 10mg $70.00 · TFC Peptides 10mg $55.00

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

NNMT transfers a methyl group from S-adenosylmethionine to nicotinamide, producing 1-methylnicotinamide. Inhibiting the enzyme is hypothesized to do two things at once: preserve nicotinamide for the NAD+ salvage pathway and spare the cell's methyl-donor pool. In mouse adipocyte and diet-induced obesity experiments, 5-amino-1MQ has been associated with higher intracellular NAD+ and reduced lipogenesis, while studies in aged mice explored muscle stem-cell activity. Which downstream pathways, such as sirtuin signaling, account for these observations is still being worked out, and selectivity against related methyltransferases continues to be characterized.

Research and regulatory status

Published research on 5-amino-1MQ is limited to cell culture and rodent models, mainly from a small number of academic groups. There are no completed controlled human trials, and the compound is not an approved medicine. That makes it an early-stage tool compound. Readers should be wary of marketing claims that go beyond the preclinical data, and should judge each GLP1 Forum Escrow listing by the batch-specific lab report attached to it rather than by descriptive copy.

Checking the lab data

Because this is a small molecule, identity is best confirmed by mass spectrometry showing the quinolinium cation, ideally supported by NMR or UV spectra. The report should state which salt form is supplied, for example iodide, since the counter-ion changes the amount of active cation per milligram. HPLC purity with a chromatogram, residual solvent screening and appearance belong on the report; any amino-acid sequence or peptide-content claim would suggest a copied template.

No independent report is attached to this listing yet. You can compare brands that publish one on the marketplace or browse the lab reports directory.

Listing details

Compound: 5-Amino-1MQ
Synonyms: 5-Amino-1-Methylquinolinium
Class: Small-molecule NNMT inhibitor
Format: Lyophilized (freeze-dried) powder
Vial strength: 50mg
Vials per kit: 10
Total content: 500 mg
Price per mg: $0.245
Sold by: SynTide Research
Ships from: China
Lab report: Not yet published

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 50 mg vial dissolved in 2 mL gives 25 mg/mL, or 50 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

What does NNMT do in normal metabolism?

NNMT methylates nicotinamide, a form of vitamin B3, so that it can be excreted, and in the process it consumes methyl groups from S-adenosylmethionine. Elevated NNMT activity has been reported in adipose tissue from obese animal models and in some cancers, which is why researchers became interested in selective inhibitors.

How does 5-Amino-1MQ differ from NAD+ precursors such as NMN?

NMN is a building block that cells can convert into NAD+. 5-amino-1MQ supplies nothing itself; it is studied for blocking an enzyme that diverts nicotinamide away from NAD+ recycling. The two approach NAD+ biology from different directions, and data gathered on one should not be assumed to apply to the other.

How much 5-Amino-1MQ is in this listing?

10 vials of 50mg each — 500 mg in all. Where a lab report exists, the testing panel above shows what the brand's tested sample actually measured.

When does SynTide Research get paid?

Only after you confirm delivery. Until then the payment is held in escrow, and you can open a claim if anything is wrong with the order.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.