Name: TB-500 FRAG 10mg (10 Vials / Kit)
Brand: Uther Peptide
SKU: UP-TB-500-FARG-10MG
Price: 85.00 USD
Availability: InStock

TB-500 Fragment at a glance

Instead of the complete 43-residue Thymosin Beta-4, this product supplies only residues 17 to 23, the Leu-Lys-Lys-Thr-Glu-Thr-Gln stretch, with an acetyl group capping the N-terminus. That short motif is the part of the parent protein that contacts actin. The listed formula is C38H68N10O14, with a molecular weight of 889.01 g/mol. Some vendors sell this fragment under the TB-500 name, so it is listed separately here to avoid confusion with the full-length protein.

Price and availability

A kit of 10 vials at 10mg each (100 mg in total) from Uther Peptide, shipped from China. The price is $85.00, or $0.85 per milligram of peptide. Of the 3 TB-500 Fragment listings on the marketplace, from 3 brands, this is the lowest price per mg. Your payment waits in escrow until you confirm the parcel arrived, and only then is it released to the brand.

This listing: Uther Peptide TB-500 Fragment

Brand: Uther Peptide
Kit: 10 vials × 10 mg (100 mg in total)
Price per vial: $8.50
Price per mg: $0.85
Also sold by: HK Peptide 10mg $130.00 · TFC Peptides 10mg $85.00

Lab testing

Uther Peptide published a Janoshik report for this compound. Test: Identity & purity. Result: TB-500 frag 10mg. Tested Jul 30, 2025.

View the report · How to read it (Testing 101) · Every report for this compound

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

Thymosin Beta-4 regulates the pool of free actin monomers that cells draw on to build filaments, and the LKKTETQ motif is central to that binding. Isolating the motif lets researchers ask a structure-activity question: does this domain alone reproduce effects such as cell migration, closure of experimental wounds and growth of new blood vessels, or do other regions of the full protein contribute? Some studies report activity for the fragment in migration and wound assays, while other effects of the parent protein may depend on additional sequence.

Research and regulatory status

Work with the fragment is preclinical and centered on cell-migration assays, wound models and side-by-side comparisons with the full-length protein. It has not been tested in controlled human trials and has no approval as a medicine. Like the parent protein, Thymosin Beta-4 derivatives fall under the World Anti-Doping Agency prohibited list. The literature on the fragment is considerably smaller than for full-length Thymosin Beta-4.

Checking the lab data

The decisive check is mass spectrometry matching the acetylated heptapeptide at about 889 g/mol. That figure separates it from full-length Thymosin Beta-4, which is several times heavier, and from an uncapped fragment, which would be lighter by the mass of the acetyl group. HPLC purity with the chromatogram, measured content per vial and a white freeze-dried cake should be reported, along with the explicit sequence on the certificate.

This listing has an independent lab report attached; the testing panel above summarises what the tested sample contained against its label.

Listing details

Compound: TB-500 Fragment
Synonyms: Thymosin Beta-4 Fragment (17-23), Ac-LKKTETQ
Class: Acetylated actin-binding heptapeptide fragment
Format: Lyophilized (freeze-dried) powder
Molecular formula: C₃₈H₆₈N₁₀O₁₄
Molecular weight: 889.01 g/mol
Vial strength: 10mg
Vials per kit: 10
Total content: 100 mg
Price per mg: $0.85
Sold by: Uther Peptide
Ships from: China
Lab report: Independent report attached

Storage and preparation

Keep unopened freeze-dried vials cold, sealed and out of the light; moisture is what degrades a lyophilized cake fastest. After reconstitution, refrigerate the solution and work within the stability window your protocol sets.

Concentration arithmetic: one 10 mg vial dissolved in 2 mL gives 5 mg/mL, or 10 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Why use a fragment instead of the full protein?

A short fragment is easier to synthesize and characterize, and it isolates one functional region. That makes it useful for asking whether a particular biological effect depends on the actin-binding motif alone. If the fragment reproduces an effect, the motif is implicated; if it does not, other parts of the full protein are likely involved.

Why is the N-terminus acetylated?

The acetyl cap removes the positive charge at the start of the chain, so the fragment behaves more like the same stretch embedded within a longer protein. Capping can also make short peptides less vulnerable to enzymes that trim from the N-terminal end. It changes the mass slightly, so the lab report should reflect the capped form.

How much TB-500 Fragment is in this listing?

10 vials of 10mg each — 100 mg in all. Where a lab report exists, the testing panel above shows what the brand's tested sample actually measured.

What if the parcel never arrives?

Open a claim from your order page. The payment is still in escrow at that point, so a claim decided in your favour is refunded to your Escrow Wallet.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.