Name: Epithalon
Brand: Lilipeptide
SKU: LILI-epithalon
Availability: OutOfStock

Epitalon at a glance

Epitalon is a tetrapeptide with the sequence Ala-Glu-Asp-Gly, formula C14H22N4O9 and a molecular weight of 390.35 g/mol. Vladimir Khavinson's group in St. Petersburg synthesized it after analyzing the amino-acid composition of epithalamin, a pineal gland extract the group had been testing, intending a reproducible, chemically defined successor. Its small size makes it inexpensive to synthesize and simple to characterize, and it is among the most frequently listed of the bioregulator peptides.

Price and availability

Lilipeptide lists this listing, shipped from China. It is listed at $63.00. As with every order here, the brand is paid only after you confirm delivery.

This listing: Lilipeptide Epithalon

Brand: Lilipeptide
Also sold by: Vital Edge Science Epithalon $78.00 · EuropePeptide 10mg $39.99 · TFC Peptides 10mg $40.00 · Sulan Bio 10mg $80.00 · Lianhua Peptide Co. 10mg $48.60 · TFC Peptides 40mg $135.00

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

The most cited claim concerns telomerase. Work in cultured human fibroblasts and other cells reported increased expression of the catalytic telomerase subunit and longer telomeres after exposure, findings that have drawn attention but limited replication. A second thread involves the pineal gland: studies in aging animals describe restored nocturnal melatonin rhythms. The originating group also proposes that short peptides bind specific DNA sequences or histone proteins, altering chromatin accessibility and gene transcription. Changes in antioxidant enzymes have been reported too. Each of these is a hypothesis under investigation rather than a settled mechanism.

Research and regulatory status

Most studies were produced by the St. Petersburg Institute of Bioregulation and Gerontology and its collaborators: cell culture, rodent and fruit-fly lifespan experiments, and small human studies in older adults. Methodological detail in some of these papers is sparse, and large independent trials are absent. Epitalon is not approved as a medicine in the United States or the EU. Readers should weigh the literature as early-stage and concentrated within one research network.

Checking the lab data

With only four residues, Epitalon is easy to characterize but also easy to substitute. A credible report shows a mass-spectrometry result matching Ala-Glu-Asp-Gly, an HPLC chromatogram with the main peak clearly resolved and its purity stated, and a batch number tied to the vial. Look for a small, white, dense lyophilized cake. Results from an independent third-party lab carry more weight than a manufacturer's in-house sheet.

This listing has no third-party report on file yet. The lab reports directory and the Epitalon page show which brands do publish testing.

Listing details

Compound: Epitalon
Synonyms: Epithalon, Epithalamin fragment
Class: Synthetic tetrapeptide bioregulator (Ala-Glu-Asp-Gly)
Format: Lyophilized (freeze-dried) powder
Molecular formula: C14H22N4O9
Molecular weight: 390.35 g/mol
Sold by: Lilipeptide
Ships from: China
Lab report: Not yet published

Storage and preparation

Keep it sealed, at the temperature printed on the label and out of direct light; anything with a damaged seal or cloudy contents should be discarded.

Buyer questions

Why is Epitalon spelled several different ways?

Transliteration from Russian produced Epitalon, Epithalon and occasionally Epithalone, and some sellers use AEDG after its one-letter sequence. These all describe the same tetrapeptide. Searching each spelling helps when gathering literature, and checking the sequence on the analytical report confirms that the vial matches the name.

Has Epitalon's telomerase effect been independently confirmed?

Only partially. Most reports come from the originating group or its close collaborators, and independent laboratories have published relatively few direct replications. Telomere measurements are also technically sensitive to method. Until broader replication appears, the telomerase findings are best viewed as intriguing preliminary results rather than an established property.

When does Lilipeptide get paid?

Only after you confirm delivery. Until then the payment is held in escrow, and you can open a claim if anything is wrong with the order.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.