5-Amino-1MQ 5mg (10 Vials / Kit)

5-Amino-1MQ at a glance

5-Amino-1-methylquinolinium is a small aromatic cation rather than a chain of amino acids, even though it is sold alongside peptides. It emerged from structure-activity work on quinolinium analogues aimed at blocking nicotinamide N-methyltransferase, or NNMT, while still crossing cell membranes. NNMT expression is comparatively high in liver and adipose tissue. The material is offered as a freeze-dried powder for laboratory study; as a small molecule it has no amino-acid sequence, whatever a product template may suggest.

Price and availability

This is HPEBIO‘s kit of 10 vials at 5mg each (50 mg in total), dispatched from China. The price is $40.50, or $0.81 per milligram of peptide. 7 brands sell 5-Amino-1MQ on GLP1 Forum Escrow, with a typical price of $0.245–$0.81 per mg (median $0.70); this listing is inside that range. As with every order here, the brand is paid only after you confirm delivery.

What it is studied for

NNMT transfers a methyl group from S-adenosylmethionine to nicotinamide, producing 1-methylnicotinamide. Inhibiting the enzyme is hypothesized to do two things at once: preserve nicotinamide for the NAD+ salvage pathway and spare the cell's methyl-donor pool. In mouse adipocyte and diet-induced obesity experiments, 5-amino-1MQ has been associated with higher intracellular NAD+ and reduced lipogenesis, while studies in aged mice explored muscle stem-cell activity. Which downstream pathways, such as sirtuin signaling, account for these observations is still being worked out, and selectivity against related methyltransferases continues to be characterized.

Research and regulatory status

Published research on 5-amino-1MQ is limited to cell culture and rodent models, mainly from a small number of academic groups. There are no completed controlled human trials, and the compound is not an approved medicine. That makes it an early-stage tool compound. Readers should be wary of marketing claims that go beyond the preclinical data, and should judge each GLP1 Forum Escrow listing by the batch-specific lab report attached to it rather than by descriptive copy.

Checking the lab data

Because this is a small molecule, identity is best confirmed by mass spectrometry showing the quinolinium cation, ideally supported by NMR or UV spectra. The report should state which salt form is supplied, for example iodide, since the counter-ion changes the amount of active cation per milligram. HPLC purity with a chromatogram, residual solvent screening and appearance belong on the report; any amino-acid sequence or peptide-content claim would suggest a copied template.

This listing has an independent lab report attached; the testing panel above summarises what the tested sample contained against its label.

Listing details

Compound

5-Amino-1MQ

Synonyms

5-Amino-1-Methylquinolinium

Class

Small-molecule NNMT inhibitor

Format

Lyophilized (freeze-dried) powder

Vial strength

5mg

Vials per kit

10

Total content

50 mg

Price per mg

$0.81

Sold by

HPEBIO

Ships from

China

Lab report

Independent report attached

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 5 mg vial dissolved in 2 mL gives 2.5 mg/mL, or 5 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.