Name: Methylcobalamin (B12) 10mg
Brand: Lab77 Peptides
SKU: LAB-3146
Price: 36.00 USD
Availability: InStock

Vitamin B12 at a glance

Unlike the peptides elsewhere in the catalog, vitamin B12 is a small organometallic molecule. Its core is a corrin ring holding a single cobalt atom, with different chemical groups attached to that cobalt in its various forms, including cyanocobalamin, hydroxocobalamin, methylcobalamin and adenosylcobalamin. Animals cannot make it; only certain bacteria and archaea synthesize it, which is why dietary intake is central to nutritional research. Listings here are freeze-dried powders in vials.

Price and availability

A single 10mg vial from Lab77 Peptides, shipped from the United States. At $36.00 for the kit, that works out to $3.60 per mg. 2 brands currently sell Vitamin B12 here, so compare their listings before ordering. Funds stay in escrow and are released to Lab77 Peptides only when you mark the order as received.

This listing: Lab77 Peptides Vitamin B12

Brand: Lab77 Peptides
Also sold by: HK Peptide 10mg $45.00 · HK Peptide 2mg $9.00

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

Cobalamin works as a cofactor for two enzymes in human cells. Methionine synthase uses methylcobalamin to convert homocysteine to methionine, a step that links folate metabolism to the supply of methyl groups for DNA, protein and lipid methylation. Methylmalonyl-CoA mutase, in the mitochondria, uses adenosylcobalamin to process certain fatty acids and amino acids. When either step falters, homocysteine or methylmalonic acid accumulates, and researchers study the consequences for red-cell production and the maintenance of nerve tissue.

Research and regulatory status

The biology of B12 is well established compared with most research compounds. Cobalamin is an approved medicine and a common supplement, and deficiency is a recognized cause of megaloblastic anemia and nerve damage. Current research looks at absorption and transport, interactions with folate, markers for assessing status, and the roles of the different cobalamin forms. Material listed here is research-grade and not labeled or packaged as a consumer product.

Checking the lab data

A credible report should state which cobalamin form the vial contains, because cyanocobalamin, methylcobalamin and hydroxocobalamin differ in mass and stability. Identity is usually confirmed by HPLC against a reference standard, often supported by mass spectrometry or a UV-visible spectrum. Purity, measured content per vial and the appearance of the powder should be reported. Cobalamins are light-sensitive, so both the report and the packaging should reflect protection from light.

This listing has no third-party report on file yet. The lab reports directory and the marketplace show which brands do publish testing.

Listing details

Compound: Vitamin B12
Synonyms: Cobalamin
Class: Water-soluble B-vitamin (cobalt-containing)
Format: Lyophilized (freeze-dried) powder
Vial strength: 10mg
Total content: 10 mg
Price per mg: $3.60
Sold by: Lab77 Peptides
Ships from: United States
Lab report: Not yet published

Storage and preparation

Keep unopened freeze-dried vials cold, sealed and out of the light; moisture is what degrades a lyophilized cake fastest. After reconstitution, refrigerate the solution and work within the stability window your protocol sets.

Concentration arithmetic: one 10 mg vial dissolved in 2 mL gives 5 mg/mL, or 10 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

What is the difference between the cobalamin forms?

They share the same corrin-cobalt core but carry different groups on the cobalt: a cyanide group in cyanocobalamin, a hydroxyl in hydroxocobalamin, a methyl in methylcobalamin and an adenosyl group in adenosylcobalamin. The last two are the active cofactor forms in cells, while the first two are more common in manufactured products.

Why does B12 research often involve folate?

The two vitamins meet at methionine synthase, the enzyme that regenerates methionine and recycles folate into usable forms. When B12 is lacking, folate becomes stuck in a form cells cannot use, a phenomenon known as the methyl-folate trap. That shared pathway makes it hard to study either vitamin in isolation.

How much Vitamin B12 is in this listing?

One vial of 10mg. Where a lab report exists, the testing panel above shows the measured content of the tested sample.

When does Lab77 Peptides get paid?

Only after you confirm delivery. Until then the payment is held in escrow, and you can open a claim if anything is wrong with the order.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.