SS-31 10mg

SS-31 (Elamipretide) at a glance

SS-31 came out of a series of small designed peptides named after Hazel Szeto and Peter Schiller, the researchers who developed them. Its four residues, D-Arg-Dmt-Lys-Phe-NH2, alternate positive charges with aromatic rings, a pattern that lets the molecule pass through cell membranes and collect on the inner membrane of mitochondria without a carrier. The D-arginine and dimethyltyrosine (Dmt) building blocks help it resist enzymatic breakdown. In clinical development it carries the name elamipretide.

Price and availability

Sold by Purus Peptides and sent from the United States, this listing is a single 10mg vial. The price is $53.00, or $5.30 per milligram of peptide. Across 17 brands listing SS-31 (Elamipretide) here, the middle half of prices falls between $0.733 and $3.80 per mg; this kit is above the typical range. Funds stay in escrow and are released to Purus Peptides only when you mark the order as received.

What it is studied for

Its main proposed target is cardiolipin, a lipid found almost exclusively in the inner mitochondrial membrane, where it helps hold the respiratory chain complexes in place and shapes the folded cristae. SS-31 is thought to bind cardiolipin and protect it from peroxidation. In experimental systems this has been linked to better-organized cristae, more efficient electron transfer and ATP output, and less leakage of reactive oxygen species. Because the peptide acts at the membrane rather than through a cell-surface receptor, it is studied as a tool for probing mitochondrial bioenergetics directly.

Research and regulatory status

As elamipretide, the peptide has been tested in human trials in primary mitochondrial myopathy, Barth syndrome, heart failure and age-related eye disease, with mixed results across indications. In the United States it received accelerated approval for Barth syndrome, a rare inherited mitochondrial disorder, while other uses remain investigational. Preclinical studies cover ischemia-reperfusion injury, kidney disease and aging models. Research-grade SS-31 is not the approved medicine and is not interchangeable with it.

Checking the lab data

Because SS-31 is small, a mass spectrometry result near the listed 639.8 g/mol is a clear identity check, read alongside HPLC purity with the chromatogram. Swapping dimethyltyrosine for plain tyrosine would show as a mass difference, but the D-arginine configuration cannot be seen by mass alone, so chiral analysis or a supplier statement on stereochemistry adds confidence. Expect measured content per vial, a batch number, and a description of a white freeze-dried cake.

This listing has an independent lab report attached; the testing panel above summarises what the tested sample contained against its label.

Listing details

Compound

SS-31 (Elamipretide)

Synonyms

Elamipretide, Bendavia, MTP-131

Class

Mitochondria-targeted tetrapeptide

Format

Lyophilized (freeze-dried) powder

Molecular formula

C₃₂H₄₉N₉O₅

Molecular weight

639.8 g/mol

Vial strength

10mg

Total content

10 mg

Price per mg

$5.30

Sold by

Purus Peptides

Ships from

United States

Lab report

Independent report attached

Storage and preparation

Keep unopened freeze-dried vials cold, sealed and out of the light; moisture is what degrades a lyophilized cake fastest. After reconstitution, refrigerate the solution and work within the stability window your protocol sets.

Concentration arithmetic: one 10 mg vial dissolved in 2 mL gives 5 mg/mL, or 10 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.