Cagrilintide 5mg

Cagrilintide at a glance

Amylin is a peptide hormone secreted by pancreatic beta cells alongside insulin. Cagrilintide, developed by Novo Nordisk under the code AM833, is an engineered amylin analogue carrying a fatty-acid side chain that associates reversibly with albumin, slowing its removal from the circulation. Further sequence changes were introduced to reduce the tendency of native human amylin to aggregate into fibrils. Its listed molecular formula is C194H312N54O59S2, giving a molecular weight of about 4409 g/mol.

Price and availability

A single 5mg vial from Purus Peptides, shipped from the United States. The price is $47.00, or $9.40 per milligram of peptide. 17 brands sell Cagrilintide on GLP1 Forum Escrow, with a typical price of $1.73–$8.48 per mg (median $1.97); this listing is above the typical range. Checkout goes into escrow first; the funds move to Purus Peptides once delivery is confirmed.

What it is studied for

Amylin receptors are unusual: each forms when the calcitonin receptor pairs with one of the receptor activity-modifying proteins, RAMP1, RAMP2 or RAMP3. Cagrilintide is described as a nonselective agonist that activates these amylin receptor complexes and the calcitonin receptor itself. In animal and early human studies, signaling through hindbrain regions such as the area postrema has been linked to delayed gastric emptying, reduced food intake and lower post-meal glucagon. Because these pathways differ from GLP-1 receptor signaling, investigators examine the two classes side by side to separate their contributions to energy-balance endpoints.

Research and regulatory status

Clinical development has centered on the fixed combination with semaglutide, often called CagriSema, which has been evaluated in large late-stage obesity and type 2 diabetes trials. Cagrilintide on its own has been studied in a mid-stage weight-management trial. As of early 2026, neither the single agent nor the combination should be described as an approved medicine, and its regulatory position can change quickly, so readers should confirm it against current agency records. Mechanistic detail still relies heavily on rodent pharmacology.

Checking the lab data

Because cagrilintide is a large lipidated peptide, a convincing report pairs HPLC purity with high-resolution mass spectrometry showing a deconvoluted mass close to 4409 Da, which confirms the fatty-acid side chain is present. A missing or truncated lipid would show up as a lower mass. Peptide-content figures help when comparing listings per mg. Expect a white lyophilized cake; solutions prepared for analysis should be clear, and turbidity or gel-like residue suggests aggregation.

This listing has an independent lab report attached; the testing panel above summarises what the tested sample contained against its label.

Listing details

Compound

Cagrilintide

Synonyms

CAGRI, AM833

Class

Long-acting amylin receptor agonist

Format

Lyophilized (freeze-dried) powder

Molecular formula

C₁₉₄H₃₁₂N₅₄O₅₉S₂

Molecular weight

4409.0 g/mol

Vial strength

5mg

Total content

5 mg

Price per mg

$9.40

Sold by

Purus Peptides

Ships from

United States

Lab report

Independent report attached

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Concentration arithmetic: one 5 mg vial dissolved in 2 mL gives 2.5 mg/mL, or 5 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.