Name: Semax 10mg (10 Vials / Kit)
Brand: European Peptide Sciences
SKU: EP-SEMAX
Price: 330.00 USD
Availability: InStock

Semax at a glance

Semax is a synthetic heptapeptide with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. Its first four residues match the 4-7 segment of adrenocorticotropic hormone, and the added Pro-Gly-Pro tail slows breakdown by peptidases. It was developed by researchers at the Institute of Molecular Genetics in Moscow. Although it descends from ACTH, it is not treated as a hormonal peptide, because the shortened sequence no longer carries the adrenal-stimulating activity of the parent molecule.

Price and availability

A kit of 10 vials at 10mg each (100 mg in total) from European Peptide Sciences, shipped from the Netherlands. At $330.00 for the kit, that works out to $3.30 per mg. Across 20 brands listing Semax here, the middle half of prices falls between $0.60 and $3.30 per mg; this kit is inside that range. Your payment waits in escrow until you confirm the parcel arrived, and only then is it released to the brand.

This listing: European Peptide Sciences Semax

Brand: European Peptide Sciences
Kit: 10 vials × 10 mg (100 mg in total)
Price per vial: $33.00
Price per mg: $3.30
Also sold by: Jinlu Peptides 10mg $153.00 · BioPepta 10mg $51.00 · HPEBIO 10mg $60.00 · AUverifiedPeptides 10mg $280.00 · Zyn Pharma 10mg $320.00 · UWA Biotech 10mg $95.00

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

Much of the mechanistic literature centers on neurotrophins. Rodent studies report that Semax raises levels of brain-derived neurotrophic factor and its receptor TrkB in the hippocampus and cortex, and gene-expression work after experimental ischemia describes shifts in inflammatory and vascular transcripts. Other papers propose effects on dopamine and serotonin turnover and possible interactions with melanocortin receptors, which would fit its ACTH ancestry. Antioxidant-like activity has also been described. How these observations connect, and which matter most, has not been settled, and the data come chiefly from animal tissue.

Research and regulatory status

Semax holds a different regulatory position from most catalogue peptides. Russian authorities list it as a registered medicine, supplied as nasal drops, and clinical reports from Russia cover stroke and cognitive disorders. Those studies are mostly small and published in Russian-language journals, which limits outside scrutiny. Semax has not been approved by the FDA or the EMA, and in the United States and Europe it is handled as an unapproved research compound with a largely preclinical evidence base.

Checking the lab data

Identity is best confirmed by mass spectrometry showing the mass expected for Met-Glu-His-Phe-Pro-Gly-Pro, with any N-acetyl or amidated variant stated explicitly when a vendor sells a modified form. HPLC purity should come from a chromatogram, not a bare figure. Because the sequence contains methionine, oxidized impurities are a known risk, so a clean main peak matters. Expect a white, intact lyophilized cake and a batch-matched, dated report.

No independent report is attached to this listing yet. You can compare brands that publish one on the Semax page or browse the lab reports directory.

Listing details

Compound: Semax
Synonyms: ACTH(4-10) analog
Class: Synthetic ACTH-fragment neuropeptide
Format: Lyophilized (freeze-dried) powder
Vial strength: 10mg
Vials per kit: 10
Total content: 100 mg
Price per mg: $3.30
Sold by: European Peptide Sciences
Ships from: Netherlands
Lab report: Not yet published

Storage and preparation

Keep unopened freeze-dried vials cold, sealed and out of the light; moisture is what degrades a lyophilized cake fastest. After reconstitution, refrigerate the solution and work within the stability window your protocol sets.

Concentration arithmetic: one 10 mg vial dissolved in 2 mL gives 5 mg/mL, or 10 mg/mL in 1 mL. The Research Lab calculator in your dashboard handles any other volume.

Buyer questions

What is the difference between Semax and N-acetyl Semax?

N-acetyl Semax carries an acetyl group on the N-terminal methionine, a change intended to further slow enzymatic degradation. Some listings add an amide at the C-terminus as well. These are distinct molecules with different masses, so the analytical report should state exactly which form was tested.

Why does the Pro-Gly-Pro ending matter?

Short ACTH fragments are cleared by peptidases very quickly. The Pro-Gly-Pro extension was added to make the peptide more resistant to that breakdown, and the tripeptide itself has been studied separately for activity of its own. Its presence is one reason Semax persists long enough to be measured in tissue studies.

How much Semax is in this listing?

10 vials of 10mg each — 100 mg in all. Where a lab report exists, the testing panel above shows what the brand's tested sample actually measured.

When does European Peptide Sciences get paid?

Only after you confirm delivery. Until then the payment is held in escrow, and you can open a claim if anything is wrong with the order.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.