Name: Ara-290
Brand: Lilipeptide
SKU: LILI-ara-290
Price: 79.00 USD
Availability: InStock

ARA-290 at a glance

Erythropoietin has two jobs: driving red blood cell production and, separately, protecting stressed tissue. ARA-290, given the nonproprietary name cibinetide, was designed by Araim Pharmaceuticals to capture the second role alone. Its 11 residues mimic the three-dimensional surface of EPO's helix B, a face that does not take part in hematopoietic receptor binding. Its reported molecular weight is around 1257 g/mol, and research material is supplied as a lyophilized powder.

Price and availability

Sold by Lilipeptide and sent from China, this listing is a listing. It is listed at $79.00. Checkout goes into escrow first; the funds move to Lilipeptide once delivery is confirmed.

This listing: Lilipeptide ARA-290

Brand: Lilipeptide
Also sold by: Lab77 Peptides 10mg $50.00 · HK Peptide 10mg $85.00 · TFC Peptides 10mg $55.00 · Uther Peptide 16mg $105.00

Lab testing

There is no public lab report for this listing yet. We can ask the brand for the batch COA before you order. Many buyers also split an independent HPLC test with others who bought the same batch.

Request the batch COA · How group testing works

Bought through escrow: the brand is only paid after you confirm delivery. If the parcel never arrives, or an independent test shows the wrong compound or a significant under-fill, open a claim before releasing payment.

What it is studied for

Hematopoietic signaling requires a homodimer of the EPO receptor. Tissue-protective signaling is attributed instead to a heteromeric complex in which the EPO receptor partners with the beta-common receptor, CD131, a combination called the innate repair receptor. This receptor is reported to be upregulated in injured or inflamed tissue. Engagement by cibinetide has been associated in animal models with reduced pro-inflammatory cytokine signaling, preservation of small nerve fibers and improved metabolic markers. The innate repair receptor model itself is still debated, and some researchers question whether CD131 is required in every tissue.

Research and regulatory status

Cibinetide has reached human trials, which sets it apart from most catalogue peptides. Small randomized studies in sarcoidosis-related small-fiber neuropathy and in diabetic neuropathy reported changes in corneal nerve fiber measures and symptom scores. No regulator has approved it, and larger confirmatory trials have not been published. Preclinical work continues in inflammation, retinopathy and metabolic-disease models, so it is best described as an investigational compound with early human data.

Checking the lab data

Mass spectrometry should return a mass close to the roughly 1257 g/mol cited for cibinetide, confirming the full sequence rather than a truncated or substituted peptide. Since catalogues sometimes print incomplete sequence strings, the report's sequence line deserves a careful read against the published structure. HPLC purity, the batch number and the test date from an independent lab complete the picture. The vial should contain a white lyophilized cake.

This listing has no third-party report on file yet. The lab reports directory and the marketplace show which brands do publish testing.

Listing details

Compound: ARA-290
Synonyms: Cibinetide
Class: EPO-derived innate repair receptor agonist (11-amino-acid peptide)
Format: Lyophilized (freeze-dried) powder
Sold by: Lilipeptide
Ships from: China
Lab report: Not yet published

Storage and preparation

Freeze-dried peptide keeps best sealed, cold and dark. Once it has been dissolved, refrigerate it, avoid repeated warming and follow the stability limits in your study protocol.

Buyer questions

Why is ARA-290 described as acting where tissue is already injured?

Researchers report that the innate repair receptor is expressed at low levels in healthy tissue and increases in response to injury, inflammation or metabolic stress. That pattern is proposed to explain why cibinetide's effects in animal models appear mostly in damaged tissue, though the receptor's regulation in humans is not fully characterized.

Is cibinetide the same as ARA-290?

Yes. ARA-290 is the developer's research code, and cibinetide is the international nonproprietary name assigned later. Clinical trial registries and journal articles use both, so searching each term gives a fuller view. Older papers may describe the same design as a pyroglutamate helix B surface peptide, abbreviated pHBSP.

What if the parcel never arrives?

Open a claim from your order page. The payment is still in escrow at that point, so a claim decided in your favour is refunded to your Escrow Wallet.

Supplied for laboratory research only. Not for human or veterinary use, and not a substitute for any prescription medicine. Nothing on this page is medical advice.